Colorimetric and Fluorimetric Detection of Fe(III) Using a Rhodamine-Imidazole Hydrazone Based Chemosensor: Photophysical Properties, DFT, TGA, and DSC Studies.

Rhodamine-imidazole hydrazones (RIH-1 & RIH-2) based chemosensors have been synthesized. These are characterised and evaluated by FT-IR spectroscopy, H-NMR, C-NMR, LCMS, absorption and fluorescence spectroscopy. These chemosensors exhibit enhanced sensitivity and selectivity in detecting the biologically significant Fe metal ion through both colorimetric and fluorescence changes.

Unique development of a new dual application probe for selective detection of antiparallel G-quadruplex sequences.

G-Quadruplex (G4) structures play vital roles in many biological processes; consequently, they have been implicated in various human diseases like cancer, Alzheimer's disease . The selective detection of G4 DNA structures is of great interest for understanding their roles and biological functions. Hence, development of multifunctional fluorescent probes is indeed essential.

Understanding the binding interaction between phenyl boronic acid P1 and sugars: determination of association and dissociation constants using S-V plots, steady-state spectroscopic methods and molecular docking.

Continuous monitoring of glucose and sugar sensing plays a vital role in diabetes control. The drawbacks of the present enzyme-based sugar sensors have encouraged the investigation into alternate approaches to design new sensors. The popularity of fluorescence sensors is due to their ability to bind reversibly to compounds containing diol.

Synthesis and Computational Studies on Optoelectronically Important Novel Acridin-Isoindoline-1,3-Dione Derivatives.

A series of novel 2-(4-(acridin-9-ylamino)phenyl)isoindoline-1,3-dione derivatives were designed and synthesized namely 2-(4-(4-methoxyacridin-9-ylamino)phenyl)isoindoline-1,3-dione [S1], 2-(4-(3-chloroacridin-9ylamino)phenyl)isoindoline-1,3-dione [S2], 2-(4-(2-fluor oacridin-9ylamino)phenyl)isoindoline-1,3-dione [S3], 2-(4-(1,4-dichloroacridin-9ylamino) phenyl)isoindoline-1,3-dione [S4]. The photophysical, thermal properties of these compounds were characterized by the spectroscopic and thermographic method. The absorbance and fluorescence spectra of these derivatives were recorded in different solvents to understand the role of solute and solvent interaction.