Publications by authors named "Karissa French"
Article Synopsis
- The study examined toxicological deaths in Ontario between 2018 and 2021, focusing on changes due to the COVID-19 pandemic.
- Researchers used coroner's data to analyze postmortem examinations and categorized deaths by cause and manner, isolating toxicological cases for comparison.
- Findings revealed a significant increase (22%) in deaths, with a notable rise in drug-related deaths and a dominance of fentanyl; men, particularly those aged 30-39, were disproportionately affected.
Background: Propofol is often used for sedation during colonoscopy. We assessed the impact of propofol sedation on colonoscopy related quality metrics and cost in a population-based cohort study.
Methods: All colonoscopies performed at 21 hospitals in the province of Ontario, Canada, during an 18-month period, from April 1, 2017 to October 31, 2018, using either propofol or conscious sedation were evaluated.
We present a fascinating case of a 57-year-old male with a novel mutation in MLH1 (), who presented with two synchronous colonic tumours, initially deemed unresectable, and experienced a complete pathological response on neoadjuvant pembrolizumab. Extensive genetic testing revealed post-zygotic mosaicism from the novel mutation.
View Article and Find Full Text PDFImportance: Trainees routinely participate in colonoscopy procedures, yet whether their involvement is positively or negatively associated with procedural quality is unknown because prior studies involved small number of trainees and/or supervisors, lacked generalizability, and/or failed to adjust for potential confounders.
Objective: To assess the association between trainee participation and colonoscopy quality metrics.
Design, Setting, And Participants: This multicenter population-based cohort study was conducted at 21 academic and community hospitals between April 1, 2017, and October 31, 2018, among consecutive adult patients undergoing colonoscopy.