Whole genome sequencing and phylogenetic analysis to examine acquisition of Escherichia coli clones during international travel.

International travel facilitates the acquisition and carriage of extended-spectrum beta-lactamase-producing Escherichia coli (ESBL-E). We describe genomes of predominant ESBL-E clones detected before and after travel among subjects departing from Rio de Janeiro, Brazil, during 2015-2021, and genomes publicly available from countries visited by travelers. WGS (Illumina NovaSeq) was performed on 70 ESBL-E isolates from 66 travelers (18 pre- and 52 post-travel).

Acquisition of antimicrobial resistance determinants in Enterobacterales by international travelers from a large urban setting in Brazil.

Background: Antimicrobial resistance is increased by international mobility. We present data about intestinal colonization of travelers departing from a middle-income country.

Methods: Travelers were recruited from 2015 to 2019, collected an anal stool specimen and answered a questionnaire before and after travel.

Adherence to malaria prophylaxis among travelers from a middle-income country.

Introduction: Malaria is the main cause of death by infection among travelers and is preventable through a combination of chemoprophylaxis and personal protective measures.

Methods: Travelers were interviewed by phone 28-90 days after returning, to assess adherence to pre-travel advice for malaria prevention.

Results: A total 57 travelers were included.

Preventing diseases in round-the-world travelers: a contemporary challenge for travel medicine advice.

Providing advice for travelers embarking on long-term trips poses a challenge in travel medicine. A long duration of risk exposure is associated with underuse of protective measures and poor adherence to chemoprophylaxis, increasing the chances of acquiring infections. Recently, in our clinic, we observed an increase in the number of travelers undertaking round-the-world trips.

Osteomyelitis caused by Sporothrix schenckii in an immunocompetent patient.

Sporotrichosis is the most common subcutaneous mycosis in South America and its association with zoonotic transmission remains a relevant public health problem in Rio de Janeiro, Brazil. The disease most commonly presents as subacute or chronic cutaneous lesions, although dissemination to various organs and systems occurs in rare cases, mainly in immunosuppressed individuals. This report describes a case of sporotrichosis with severe bone and subcutaneous damage in an immunocompetent patient who did not exhibit the characteristic skin lesions of sporotrichosis, including ulcers, nodules, and lymphangitis.