Giant Basal Cell Carcinoma Within a Marjolin's Ulcer: A Case Discussion.

Marjolin's ulcers are cutaneous malignancies that arise from chronic wounds, often secondary to burns. While squamous cell carcinoma is the most prevalent type, rare instances of other tumors, such as basal cell carcinoma, have occurred. These tumors are challenging to treat due to their high recurrence rate and aggressive behavior.

Strongyloidiasis Mimicking Carcinoid Syndrome in an Immunocompetent Host.

Strongyloidiasis is a parasitic infection caused by which commonly presents as an asymptomatic infection in immunocompetent patients but may cause non-specific gastrointestinal and pulmonary complaints. Here, we report the atypical presentation of strongyloidiasis in a 72-year-old Vietnamese male with shortness of breath and flushing. This case is notable for the unique presentation of cutaneous flushing, the absence of eosinophilia, and negligible microscopic findings on stool examination.

Syringocystadenoma Papilliferum of the Left Gluteal Region in an Adult Female Patient: A Case Report.

Syringocystadenoma papilliferum is a rare, benign adnexal neoplasm most often found on the scalp, head, and neck region as a solitary hairless plaque, verruca, or nodule. Lesions may arise sporadically or from a pre-existing sebaceous nevus. We report the case of a 56-year-old female who presented with an indurated multilobulated cystic mass in the left buttock region.

Directed Nucleosome Sliding during the Formation of the Simian Virus 40 Particle Exposes DNA Sequences Required for Early Transcription.

Simian virus 40 (SV40) exists as chromatin throughout its life cycle and undergoes typical epigenetic regulation mediated by changes in nucleosome location and associated histone modifications. In order to investigate the role of epigenetic regulation during the encapsidation of late-stage minichromosomes into virions, we mapped the locations of nucleosomes containing acetylated or methylated lysines in the histone tails of H3 and H4 present in the chromatin from 48-h-postinfection minichromosomes and disrupted virions. In minichromosomes obtained late in infection, nucleosomes were found carrying various histone modifications primarily in the regulatory region, with a major nucleosome located within the enhancer and other nucleosomes at the early and late transcriptional start sites.