Publications by authors named "Karina Tassiopoulos"

Article Synopsis
  • The study aimed to determine the minimum clinically important difference (MCID) for two versions of the Quality of Life in Childhood Epilepsy Questionnaire: the full 55-item version (QOLCE-55) and the shorter 16-item version (QOLCE-16).
  • Data were gathered from 74 children with epilepsy, using both anchor-based and distribution-based methods to estimate MCID values, with results indicating different scores for each version.
  • This research highlights the importance of understanding MCID values to assess whether changes in the quality of life for children with epilepsy are significant, informing better epilepsy care.
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Background And Objectives: The current Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system instructs appraisers to evaluate whether individual observational studies have sufficiently adjusted for confounding. However, it does not provide an explicit, transparent, or reproducible method for doing so. This article explores how implementing causal graphs into the GRADE framework can help appraisers and end-users of GRADE products to evaluate the adequacy of confounding control from observational studies.

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Importance: Epilepsy is a highly treatable condition for many people, but there are large treatment gaps with suboptimal seizure control in minoritized groups. The sexual and gender minority (SGM) community is at risk for health disparities, yet the burden of epilepsy in this community is not known.

Objective: To estimate the prevalence of active epilepsy among SGM people in the United States.

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