Publications by authors named "Karina Ramirez-ALarcon"

Article Synopsis
  • The study investigates the prevalence of diabesity (obesity and type 2 diabetes) and prediabesity in Chilean adults, using data from the 2016-2017 National Health Survey with nearly 5,000 participants.
  • Findings reveal that 5.7% of participants had diabesity, 3.6% had prediabesity, and 2.5% were categorized as normo-diabetic, with higher rates among women, those with lower education levels, and individuals aged 45-46.
  • The overall prevalence of prediabesity and diabesity stands at 9.3%, indicating an urgent need for preventive measures and strategies to address these health issues in the population.
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  • - The study aimed to explore how a lifestyle score, based on seven modifiable behaviors, affects all-cause mortality in the Chilean population.
  • - Participants were assigned scores ranging from 0 (less healthy) to 7 (healthiest) based on their habits, and results showed that those with lower scores had a significantly higher mortality risk over a 10.9-year follow-up period.
  • - It concludes that promoting healthier lifestyle choices through public health strategies could reduce mortality risk among Chileans, as less healthy individuals had a mortality risk 2.55 times greater than the healthiest group.
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  • A study conducted in Chile aimed to assess adherence to Food-Based Dietary Guidelines (GABA) among adolescents aged 15-19, focusing on their diet and its relationship with health metrics.
  • Only 5.6% of participants met three or more GABA recommendations, with higher compliance in water and legumes consumption, and notable differences in dietary habits between genders.
  • The findings indicate that many adolescents struggle to follow GABA guidelines, which can negatively impact their overall health and lifestyle.
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This research aimed (1) to examine the agreement between body mass index (BMI)-based nutritional status and perceived nutritional status overall and by socio-demographic factors and (2) to state the association between the accuracy of weight perception and weight control practices in the Chilean adult population. A population-based cross-sectional study was carried out with 5,192 Chilean adult participants from the Chilean National Health Survey 2016-2017. Agreement between BMI-based weight status and body weight perception for the total sample and across subgroups was determined using the weighted kappa coefficient.

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Article Synopsis
  • The study analyzes physical activity (PA) and sedentary behavior in Chile, focusing on how these factors relate to different income levels.
  • It uses data from the 2016-2017 Chilean National Health Survey, involving over 5,000 participants, to assess PA and sedentary time through self-reported income.
  • Findings show that while low-income individuals engage more in transport-related PA, they also experience higher rates of inactivity during leisure and work compared to those with higher incomes.
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  • Legumes are recommended for consumption twice a week in Chile to enhance health, but only 24% of Chilean adults currently meet this guideline.
  • The study analyzed data from over 5,000 participants and found that being a widower decreases the likelihood of complying with legume intake, while older adults (70-80 years), rural residents, and people in the Maule region were more likely to adhere to the recommendations.
  • Overall, there are notable differences in legume consumption habits based on sociodemographic factors, emphasizing the need for targeted nutritional interventions.
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Type 2 diabetes Mellitus (T2DM) prevalence has significantly increased worldwide in recent years due to population age, obesity, and modern sedentary lifestyles. The projections estimate that 439 million people will be diabetic in 2030. T2DM is characterized by an impaired β-pancreatic cell function and insulin secretion, hyperglycemia and insulin resistance, and recently the epigenetic regulation of β-pancreatic cells differentiation has been underlined as being involved.

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Background: Water is an essential nutrient for cellular homeostasis and life. Drinking ≥ 6 glasses (1.5 L/day) is the recommendation of daily water intake (RIAD).

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Cardiovascular ailments are the number one cause of mortalities throughout the globe with 17.9 million deaths per year. Platelet activation and aggregation play a crucial role in the pathogenesis of arterial diseases, including acute coronary syndrome, acute myocardial infarction, cerebrovascular transient ischemia, unstable angina, among others.

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Ageing will be one of the most significant social transformations of the 21st century worldwide. In the last 40 years, Chile has tripled its older adult population. As a result, by 2050 the country will have the highest proportion of older adults in Latin America.

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The native flora of Chile has unique characteristics due to the geographical situation of the country, with the vast desert in the North, Patagonia in the South, the Andean Mountains on the east and the Pacific Ocean on the west. This exclusivity is reflected in high concentrations of phytochemicals in the fruits and leaves of its native plants. Some examples are Aristotelia chilensis (Molina), Stuntz (maqui), Berberis microphylla G.

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Drug development is a key point in the research of new therapeutic treatments for increasing maximum drug loading and prolonged drug effect. Encapsulation of drugs into multivesicular liposomes (DepoFoam) is a nanotechnology that allow delivery of the active constituent at a sufficient concentration during the entire treatment period. This guarantees the reduction of drug administration frequency, a very important factor in a prolonged treatment.

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Mushrooms have a significant role in human diet as functional food and as a nutraceutical resource. The combination of its umami flavor, protein, vitamins, minerals and carbohydrates has meant that mushrooms could be considered a cheap food source for a long time in many countries. Moreover, mushrooms contain an excellent variety of bioactive metabolites that can be successful in both prevention and treatment of various human health hazards.

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Article Synopsis
  • - The study aimed to explore how menopause affects cardiovascular risk factors among adult women in Chile using data from the National Health Survey (2016-2017).
  • - Out of 2,139 women surveyed, 67% were menopausal, and results showed that menopausal women had significantly higher systolic blood pressure and were more likely to have hypertension and diabetes compared to non-menopausal women.
  • - Despite the increase in certain cardiovascular risks, menopause was not linked to obesity, abdominal obesity, or metabolic syndrome in the studied population.
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Background: One of the side effects of cancer treatment is a low level of physical activity (PA) due to fatigue and pain.

Aim: To quantify PA levels in Chilean people with cancer.

Material And Methods: Analysis of the National Health Survey 2016-2017 including 6,233 participants, comparing those with and without a self-report of cancer was conducted.

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  • - The study aimed to explore how nutritional status might affect the accuracy of self-reported physical activity (PA) levels in Chilean adults by comparing the International Physical Activity Questionnaire (IPAQ) to accelerometer data from ActiGraph devices.
  • - Results showed that the IPAQ generally underestimated light PA and total PA while overestimating moderate and vigorous PA levels compared to accelerometer measurements, indicating significant discrepancies.
  • - Particularly in obese individuals, the underestimation of total PA levels was less severe than in those of normal weight, suggesting that subjects' weight may influence their self-reported activity levels.
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Alstonia sholaris is an evergreen tree commonly found in South East Asia. In traditional medicine pharmacological activities are attributed to the leaves and bark of this plant. The aim of this study is characterizing the chemicals present in A.

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Alstonia venenata is a plant commonly found in South India and used in traditional medicine. The aim of this study was to characterize the phytochemicals present in A. venenata leaf and bark extracts and study their antimicrobial activities.

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Moringa oleifera is a tree native to tropical and subtropical regions of South India and used in traditional medicine. The aim of this study was characterize the phytochemicals present in M. oleifera leaf extracts and study their antimicrobial activities.

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Diabetes mellitus is one of the major health problems in the world, the incidence and associated mortality are increasing. Inadequate regulation of the blood sugar imposes serious consequences for health. Conventional antidiabetic drugs are effective, however, also with unavoidable side effects.

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Oral mucosal lesions have many etiologies, including viral or bacterial infections, local trauma or irritation, systemic disorders, and even excessive alcohol and tobacco consumption. Folk knowledge on medicinal plants and phytochemicals in the treatment of oral mucosal lesions has gained special attention among the scientific community. Thus, this review aims to provide a brief overview on the traditional knowledge of plants in the treatment of oral mucosal lesions.

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