Evaluation of Super Refined™ Polysorbate 20 With Respect to Polysorbate Degradation, Particle Formation and Protein Stability.

Super Refined™ and Tween™ 20 HP polysorbate 20 (PS20) are two commercially available compendial grades of PS20 frequently used in biopharmaceutical formulations as protein stabilizing surfactants. PS20 degradation has been a major concern recently for potentially limiting drug product shelf life due to free fatty acid particle formation. This work is a side-by-side comparison of SR and HP PS20 in terms of PS20 degradation, particle formation and protein stability.

Prevalence of violence in childhood and adolescence and the impact on educational outcomes: evidence from the 2013 Peruvian national survey on social relations.

Background: This study provides, for the first time, national population-based estimates describing violence during childhood and adolescence in Peru and the impact on educational outcomes.

Methods: A population-based school survey was conducted among children aged 9-11 (n=1587) and adolescents aged 12-17 (n=1489). The relationship between violence and educational outcomes were analysed using bivariate logistic regressions, controlling for potential confounding factors.

Participation in Emergencies: Children's Perspective.

This article has as its objective the identification and analysis of child participation, from the point of view of the children, in the village of La Garita-Chincha, close to the epicenter of the 2007 earthquake. Ten children (six girls and four boys), aged between 8 and 12 years old, took part in the study. The results allow us to see the children as owners of capabilities to develop diagnostics about their rights, resources, and perceived needs.

Corneal endothelial safety after ultraviolet light treatment of the light-adjustable intraocular lens.

Purpose: To assess the safety to the corneal endothelium of ultraviolet (UV) light treatment to a light-adjustable intraocular lens (IOL).

Setting: Codet Vision Institute, Tijuana, Mexico.

Design: Cohort study.

Early postoperative pain following Epi-LASIK and photorefractive keratectomy: a prospective, comparative, bilateral study.

Purpose: To compare postoperative pain associated with epi-LASIK versus photorefractive keratectomy (PRK).

Methods: This prospective observer-masked randomized study included 40 eyes of 20 patients with myopia and astigmatism who received epi-LASIK (Moria Epi-K) in one eye and PRK in the contralateral eye. Corneal ablation was done using the NIDEK EC-5000 excimer laser.