Publications by authors named "Karina Lorenzo-Lorenzo"
Purpose: To evaluate the effectiveness, adverse reactions, and adherence to treatment of hypolipidemic inhibitors of proprotein convertase subtilisin/kexin type 9 (PCSK9is) in a context of real clinical practice.
Methods: We present an observational, retrospective, descriptive, multicenter study of patients with hypercholesterolemia who began treatment with PCSK9is between January 2017 and December 2019, with a minimum treatment period of 3 months. The main variable we recorded was the frequency of cardiovascular events (cardiovascular death, myocardial infarction, stroke, coronary revascularization, and hospitalization for unstable angina) in patients treated with PCSK9is.
Article Synopsis
- The study analyzed potential drug-drug interactions (pDDIs) in COVID-19 patients, focusing on those treated with specific medications during the first wave of the pandemic.
- Out of 350 patients, 62.3% had at least one pDDI, with significant impacts noted on the QTc interval in a small fraction of patients, indicating potential risks.
- While the incidence of pDDIs was high, clinically significant adverse effects were relatively low, highlighting the need for careful monitoring of drug interactions in COVID-19 treatment.
Hospital Pharmacy Service (HPS) in Spain have been impacted by the health crisis caused by the COVID-19 pandemic. Thus, the outbreak has forced HPSs to adapt their outpatient consultation services to Telepharmacy to optimize clinical outcomes and reduce the risk of contagion. The purpose of this article is to describe and analyze the experience of HPSs with outpatient Telepharmacy during the COVID-19 pandemic and expose the lessons learned.
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