Intravitreal faricimab as an adjuvant in the management of tubercular uveitis.

Purpose: To report the use of intravitreal faricimab used as an adjunct in the management of intraocular tuberculosis (IOTB) in a patient with occlusive retinal vasculitis (ORV) and choroiditis.

Methods: A case report.

Results: A 27-year-old Asian male presented with bilateral choroiditis and ORV complicated by retinal neovascularization and vitreous hemorrhage in one eye.

Retinal relaxation following membrane peeling: Effect on vision, central macular thickness, and vector analysis of motion.

Background: Epiretinal membranes (ERM) form as a result of an inward displacement of retinal structures. Removal of an ERM leads to the outward displacement of retinal vessels and visual improvement.

Purpose: The aim of the study was to evaluate the direction and extent of displacement of retinal/superficial vascular structures after a membrane peeling procedure by means of image comparison and in selected cases, a vector analysis of displacement.

Intravitreal methotrexate in the management of presumed tuberculous serpiginous-like choroiditis.

Purpose: To report on the use of intravitreal methotrexate (IVT MTX) as part of treatment of presumed tuberculous serpiginous-like choroiditis progressing despite the use of tuberculostatics.

Methods: Case series of patients suffering from serpiginous-like choroiditis with positive tuberculin skin test who received IVT injections of MTX as part of treatment. Ocular disease was active despite the use of systemic tuberculostatic (isoniazid, rifampicin, pyrazinamide, and ethambutol), and choroidal lesions showed signs of progression.

Cataract surgery with primary intraocular lens implantation in children with uveitis: long-term outcomes.

Purpose: To report long-term outcomes of cataract surgery with primary posterior chamber intraocular lens (IOL) implantation in children with chronic uveitis.

Setting: Department of Ophthalmology, Pitié-Salpêtrière Hospital, Paris, France.

Design: Case series.

Intravitreal bevacizumab as first local treatment for uveitis-related choroidal neovascularization: long-term results.

Purpose: To report long-term results of intravitreal (IVT) bevacizumab as first local treatment for choroidal neovascularization (CNV) secondary to uveitis.

Methods: Files of patients receiving 1.25 mg/0.

The role of steroids in the management of uveitic macular edema.

Purpose: To review the role of steroids in the management of uveitic macular edema.

Methods: Review of recent literature on the physiopathology of macular edema and clinical trials involving steroids as main treatment of uveitic macular edema.

Results: The steroid-glucocorticoid receptor complex regulates the action of specific steroids allowing transactivation or repression of a common as well as a unique set of genes.

Uveitis related to juvenile idiopathic arthritis: familial cases and possible genetic implication in the pathogenesis.

Purpose: To describe four cases of familial Juvenile Idiopathic Arthritis (JIA) associated uveitis.

Design: Retrospective observational case series.

Methods: Clinical data from patients who present familial JIA-associated uveitis are described and possible genetic influence in disease etiology is reviewed.

Cannabinoid receptors in conjunctival epithelium: identification and functional properties.

Purpose: Preservation of the ocular surface barrier requires complex control of epithelial cell proliferation and inflammation mechanisms. The endocannabinoid system may be regulating these processes. Therefore, the authors explored the presence and properties of cannabinoid receptors (CB1 and CB2) in conjunctival epithelial cells.