Publications by authors named "Karina Corona-Cervantes"
Introduction: An obesogenic diet, a diet high in saturated fats and sugars, is a risk factor for the development of multiple obesity-related diseases. In this study, our aim was to evaluate the effect of supplementation with a mixture of Mexican functional foods (MexMix), (nopal), , and (edible crickets), compared with a high-fat and fructose/sucrose diet on an obesogenic mice model.
Methods: For this study, 18 male C57BL/6J mice were used, which were divided into three groups: (1) control group: normal diet (ND), (2) HF/FS group: high-fat diet along with 4.
Gestational diabetes (GD), pre-gestational diabetes (PD), and pre-eclampsia (PE) are morbidities affecting gestational health which have been associated with dysbiosis of the mother's gut microbiota. This study aimed to assess the extent of change in the gut microbiota diversity, short-chain fatty acids (SCFA) production, and fecal metabolites profile in a sample of Mexican women affected by these disorders. Fecal samples were collected from women with GD, PD, or PE in the third trimester of pregnancy, along with clinical and biochemical data.
View Article and Find Full Text PDFCOVID-19 is a severe respiratory disease threatening pregnant women, which increases the possibility of adverse pregnancy outcomes. Several recent studies have demonstrated the ability of SARS-CoV-2 to infect the mother enterocytes, disturbing the gut microbiota diversity. The aim of this study was to characterize the entero-mammary microbiota of women in the presence of the virus during delivery.
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- Alzheimer's disease (AD) is a complex condition linked to factors like β-amyloid deposits, Tau protein modifications, inflammation, and memory loss, with changes in gut bacteria potentially playing a role in its development.* -
- Research on offspring mice exposed to altered gut microbiota (BGM) during pregnancy and lactation showed that these changes impacted levels of Aβ and Tau proteins and spatial memory as they matured.* -
- The study highlights that specific bacterial populations in the gut may help mitigate neuroinflammation and cognitive decline by influencing brain health and promoting beneficial metabolic pathways in the context of AD.*
Article Synopsis
- Mammary gland secretory cells in humans produce milk rich in miRNAs, which are important for infant development and immune system maturation.
- This study aimed to compare the levels of specific immunoregulatory miRNAs in human colostrum and milk with those in infant milk formula.
- Results showed that these miRNAs are consistently present in human milk at higher levels than in formula, indicating their potential importance for infant health.
Obesity is a multifactorial disease resulting in excessive accumulation of fat. Worldwide, obesity is an important public health problem, affecting a large proportion of the world population. The tender cactus , commonly known in Mexico as "nopal", is widely distributed in this country, Latin America, South Africa, and the Mediterranean area.
View Article and Find Full Text PDFCoronavirus disease 2019 (COVID-19) is a disease produced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and it is currently causing a catastrophic pandemic affecting humans worldwide. This disease has been lethal for approximately 3.12 million people around the world since January 2020.
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- The microbiota acquired during birth and early life is crucial for the development of the newborn's immune system, influenced by probiotics and prebiotics from maternal milk.
- The research utilized IgA-Seq to examine the binding of immunoglobulin A (IgA) to specific bacteria in human colostrum and neonate feces, identifying diverse IgA+ bacteria.
- The findings suggest that maternal IgA2 preferentially targets certain commensal bacteria, influencing the neonatal gut microbiome's composition during the initial days of life.
Article Synopsis
- *Methods involved collecting nasopharyngeal swabs from 133 mothers and 131 neonates, along with 140 colostrum samples, to check for SARS-CoV-2 using qPCR.
- *Results showed that 12.5% of asymptomatic pregnant women and 8.3% of neonates tested positive for SARS-CoV-2, indicating possible perinatal transmission, although no significant associations were found with maternal or newborn metadata.
Article Synopsis
- Human milk is the ideal nutrition for infants, but when breastfeeding isn't feasible, pasteurized milk from human milk banks is the next best option; however, little research exists on how pasteurization affects the bacterial microbiota in human milk.
- This study aimed to compare the bacterial composition and diversity in milk from Mexican mothers both before and after Holder pasteurization using advanced DNA sequencing techniques.
- Results showed that pasteurization actually increased bacterial diversity, with specific bacteria thriving post-treatment that pose no risk to infants, indicating that the pasteurization process is safe and beneficial.
Background: Human milk microbiota plays a role in the bacterial colonization of the neonatal gut, which has important consequences in the health and development of the newborn. However, there are few studies about the vertical transfer of bacteria from mother to infant in Latin American populations.
Methods: We performed a cross-sectional study characterizing the bacterial diversity of 67 human milk-neonatal stool pairs by high-throughput sequencing of V3-16S rDNA libraries, to assess the effect of the human milk microbiota on the bacterial composition of the neonate's gut at early days.