Publications by authors named "Karina A Oganyan"
Mol Clin Oncol
April 2024
Article Synopsis
- Single-agent immune checkpoint inhibitors (ICIs) are commonly used for treating metastatic non-small cell lung cancer (NSCLC) after chemotherapy, but only some patients respond effectively.
- A study involving 181 patients identified factors like poor performance status, never-smoking history, and a high neutrophil-to-lymphocyte ratio (NLR) that were linked to shorter survival and worse outcomes.
- Patients with favorable conditions (NLR <4.3, good performance status, and past smoking) had the best responses to ICIs, while those with poor indicators had significantly worse results, demonstrating the potential for personalized treatment predictions.
