Publications by authors named "Karin van Veghel"
Omidubicel (nicotinamide-expanded cord blood) is a potential alternative source for allogeneic hematopoietic cell transplantation (HCT) when an HLA-identical donor is lacking. A phase I/II trial with standalone omidubicel HCT showed rapid and robust neutrophil and platelet engraftment. In this study, we evaluated the immune reconstitution (IR) of patients receiving omidubicel grafts during the first 6 months post-transplant, as IR is critical for favorable outcomes of the procedure.
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- The CLN3 disease can affect kids and may be serious, causing issues in the brain or just the retina.
- This study looked at a specific cell feature called lymphocyte vacuolization to see if it can help show how severe the disease is.
- By measuring this feature, researchers found that it can help tell apart different types of CLN3 disease, which might help doctors understand new genetic information and create better treatments.
Objective: IL-4 plus IL-10 prevents blood-induced cartilage damage. The aim of the present study was to evaluate whether cartilage damage can still be averted by addition of IL-4 plus IL-10 when added after the onset of a bleed and whether aspiration of blood prior to addition of IL-4 plus IL-10 is of additive protective value.
Methods: Healthy canine hip and human shoulder cartilage was exposed to whole blood for 4 days.