Genes targeted by the estrogen and progesterone receptors in the human endometrial cell lines HEC1A and RL95-2.

Background: When the steroid hormones estrogen and progesterone bind to nuclear receptors, they have transcriptional impact on target genes in the human endometrium. These transcriptional changes have a critical function in preparing the endometrium for embryo implantation.

Methods: 382 genes were selected, differentially expressed in the receptive endometrium, to study their responsiveness of estrogen and progesterone.

Expression of NGF and GDNF family members and their receptors during peripheral nerve development and differentiation of Schwann cells in vitro.

Ligands of NGF and GDNF families of neurotrophic factors have important functions in the development of the vertebrate peripheral nervous system (PNS). It has been established that they also play key roles in the regeneration of PNS. Expression patterns of NGF and GDNF family members and their receptors have mostly been analyzed during regeneration, and less during development of the PNS.