Publications by authors named "Karin Strand"
In the present study we describe an outbreak where PVL positive MRSA belonging to spa-type t002 and multi-locus sequence type ST2659 persisted in a Swedish dairy herd for at least two years, despite efforts to hinder transmission between animals and between the farmer and his animals. This is the first description of persistence and spread of MRSA in a dairy herd in Sweden. Sampling of animals in the herd was initiated by the finding of MRSA in the farmer and was performed at eight occasions from November 2012 to September 2014.
View Article and Find Full Text PDFHypernatremia in ICU is common, both as a preexisting condition and acquired during intensive care. Hypernatremia increases mortality and morbidity as an increased length of a stay and increased risk of complications. Current treatment options of manifest hypernatremia are limited, but there are opportunities for prevention that should not be overlooked.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the role of tonic extrasynaptic NMDA receptors (NMDARs) in rat hippocampal slices using reversible blockers, memantine and PCP.
- Memantine at 10 μM did not affect synaptic responses but reduced tonic NMDAR currents in GABAergic interneurons by about 50%, impacting their excitability and leading to reduced inhibition in pyramidal cells.
- The findings suggest that tonic NMDAR activity plays a more significant role in GABAergic interneurons than in pyramidal cells, which may help understand memantine’s effects in Alzheimer’s treatment.