The determination of bromide in a local anaesthetic hydrochloride by capillary electrophoresis using direct UV detection.

The determination of residual amounts of bromide in a local anaesthetic hydrochloride by capillary electrophoresis was developed. Direct UV detection at 200 nm was used for the determination of the bromide content. The separation capacity of the system must be sufficient when bromide is determined in the presence of a large excess of chloride since electromigration dispersion of the highly concentrated chloride peak may impair the resolution.