Risk factors for impulse control disorders and related behaviors in Parkinson's disease: secondary analyses of the ICARUS study.

Impulse control disorders and related behaviors (ICDs) are common in patients with Parkinson's disease (PD), yet incidence and predictive factors are not fully understood. We examined the epidemiology of ICDs in PD through secondary and analyses of data from the ICARUS (SP0990) study, which enrolled >1000 patients. Using a modified-Minnesota Impulsive Disorders Interview (mMIDI), ICD incidence was calculated for patients who were ICD-negative at baseline but ICD-positive at year 1, and year 1 and/or 2 (cumulative 2-year ICD incidence).

ICARUS study: prevalence and clinical features of impulse control disorders in Parkinson's disease.

Background: Impulse control disorders/other compulsive behaviours ('ICD behaviours') occur in Parkinson's disease (PD), but prospective studies are scarce, and prevalence and clinical characteristics of patients are insufficiently defined.

Objectives: To assess the presence of ICD behaviours over a 2-year period, and evaluate patients' clinical characteristics.

Methods: A prospective, non-interventional, multicentre study (ICARUS (Impulse Control disorders And the association of neuRopsychiatric symptoms, cognition and qUality of life in ParkinSon disease); SP0990) in treated Italian PD outpatients.