Publications by authors named "Karin Allenspach-Jorn"
Article Synopsis
- DNA shotgun sequencing and qPCR are used to study changes in the gut bacteria of dogs, with qPCR providing specific quantification of bacteria.
- The canine dysbiosis index (DI), a mathematical tool based on qPCR data, evaluates fecal microbiota differences among dogs and is correlated with changes seen in sequencing.
- Results show that dogs with a dysbiosis index indicating an imbalance in microbiota have lower diversity in their gut bacteria, and higher DI values correspond to more significant microbiota shifts, marking qPCR-based DI as a reliable indicator for these changes.
Introduction: Glucose hypometabolism and tau formation are key features of Alzheimer's disease (AD). Less is known about the relationship between fasting glucose and regional tau accumulation.
Methods: Cerebrospinal fluid (CSF) glucose was linearly regressed on regional tau (flortaucipir) among 169 Alzheimer's Disease Neuroimaging Initiative (ADNI3) participants.
Background: Obesity in midlife and early late-life is associated with worse normal cognitive aging. Dual-energy X-ray absorptiometry (DEXA) suggests that visceral adipose mass (VAM) plays a predominant role, whereas non-visceral adipose mass (NVAM) and lean muscle mass (LMM) have shown conflicting relationships. It is unknown how longitudinal, cognitive changes in age-sensitive domains like fluid intelligence (FI) correspond to VAM, NVAM, and LMM in women and men.
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