Changes in pneumococcal serotypes distribution and penicillin resistance in healthy children five years after generalization of PCV10.

Objective: () nasopharyngeal carriage has significantly decreased after the generalization of pneumococcal vaccination worldwide. This study sought to investigate changes in carriage rates, serotype distribution and penicillin non-susceptibility following the generalization of 10-valent pneumococcal conjugate vaccine.

Methods: A prospective study was conducted in Marrakesh, Morocco, between 2017 and 2018, among healthy children attending vaccination centers.

Hyperammonemia induced gut microbiota dysbiosis and motor coordination disturbances in mice: new insight into gut‑brain axis involvement in hepatic encephalopathy.

Hepatic encephalopathy (HE) is a neuropsychiatric hepatic‑induced syndrome in which several factors are involved in promoting brain perturbations, with ammonia being the primary factor. Motor impairment, incoordination, and gut dysbiosis are some of the well‑known symptoms of HE. Nevertheless, the link between the direct effect of hyperammonemia and associated gut dysbiosis in the pathogenesis of HE is not well established.

Antibiotic Resistance of in the Nasopharynx of Healthy Children Less than Five Years Old after the Generalization of Pneumococcal Vaccination in Marrakesh, Morocco.

() remains one of the most important pathogens causing childhood infections. The spread of antibiotic-resistant bacteria is a leading cause of treatment failure in children. The purpose of this investigation is to report the antibiotic and multidrug resistance (MDR) of strains isolated from healthy children throughout the years 2020-2022.

Serotype distribution and antimicrobial resistance of among children with acute otitis media in Marrakech, Morocco.

Background And Objectives: is one of the most frequent pathogens leading to a variety of clinical manifestations. The effects of carriage on acute otitis media (AOM) are poorly studied. The study aimed to assess the serotype's distribution and antimicrobial susceptibility in children with AOM after the implementation of the pneumococcal conjugate vaccine (PCV) in Morocco.

Antibiotic resistance and serotype distribution of nasopharyngeal isolates of Streptococcus pneumoniae from children in Marrakech region (Morocco).

Monitoring of Streptococcus pneumoniae antibiotic resistance is of great importance due to the frequency of strains becoming increasingly resistant to antibiotics. In this study, we report the antibiotic susceptibility of the serotypes of S. pneumoniae strains isolated from healthy children aged 1-24 months in the Marrakech region of Morocco.