Clinical success of intrauterine insemination cycles is affected by the sperm preparation time.

Objective: To determine the impact of the time interval from the end of sperm preparation (TSP) to intrauterine insemination (IUI) on the outcome.

Design: Prospective multicentre cohort study.

Setting: Seven French centers (assisted reproduction group in northeastern France, four academic centers, and three clinics).

Removal of etonogestrel contraceptive implants in the operating theater: report on 28 cases.

Objectives: We describe removal procedures for etonogestrel contraceptive implants in the operating theater. In addition, we discuss the management of removal of contraceptive implants that are difficult to palpate or are impalpable.

Design: We conducted a retrospective single-center case series analysis of Implanon removals conducted at a university hospital between January 2002 and April 2005.

Consistency of medical abortion efficacy from 5 through 14 weeks' gestation.

Objective: To assess the efficacy of medical abortion performed according to a single protocol from 5 through 14 weeks.

Study Design: Retrospective observational study of medical abortions through 14 weeks performed from January 2000 through August 2001. The protocol combined 400mg of mifepristone orally, followed 48 h later by 800 microg of misoprostol, administered vaginally, and repeated after 4 h if the patient did not begin to abort.

Assisted reproduction techniques for HIV serodiscordant couples: 18 months of experience.

Background: Assisted reproduction techniques can minimize the risk of infection and treat possible sterility associated with serodiscordant couples.

Methods: We assessed the efficacy of these techniques in 57 couples in which at least one partner had human immunodeficiency virus (HIV-1) infection that was currently under control (47 men and 10 women). The semen of seropositive men was prepared and tested for viruses.

Preimplantation genetic diagnosis for achondroplasia: genetics and gynaecological limits and difficulties.

Background: We report the first attempts at preimplantation genetic diagnosis (PGD) and IVF and their accompanying difficulties for achondroplasia (ACH) patients.

Methods: A PGD test was developed using fluorescent single cell PCR on lymphoblasts from patients and controls and from blastomeres from surplus IVF embryos. A specific digestion control based on the use of two fluorochromes was elaborated.