Effect of Tibial Slope on Coronal Alignment in Total Knee Arthroplasty.

Malalignment of total knee arthroplasty (TKA) components affects function and survivorship. Common practice is to set coronal alignment prior to adjusting slope. With improper jig placement, adjustment of the slope may alter coronal alignment.

Increasing incidence of melanoma among young adults: an epidemiological study in Olmsted County, Minnesota.

Objective: To identify the change in the incidence of cutaneous melanoma over time among young adults.

Patients And Methods: Using Rochester Epidemiology Project data, we identified patients aged 18 to 39 years who had a first lifetime diagnosis of melanoma from January 1, 1970, through December 31, 2009, in Olmsted County, Minnesota. Demographic and clinical information, including survival, was abstracted, and estimates of the incidence of melanoma and overall and disease-specific survival were generated.