A Case of Multisystem Inflammatory Syndrome in Children Presenting as Acute Appendicitis and Pancreatitis.

Multisystem Inflammatory Syndrome in Children (MIS-C) is characterized by an inflammation with fever, elevated inflammatory markers, conjunctivitis, rash, impaired coagulation, gastrointestinal symptoms and cardiac abnormalities that may progress to multiorgan failure. The presence of a positive COVID-19 antigen via a PCR test, serological testing for antibodies or close contact with a person diagnosed with COVID-19 helps differentiate MIS-C from other diseases. Gastrointestinal symptoms are recognized to be associated with COVID-19 infection or MIS-C in children, presenting as abdominal pain, gastrointestinal infection with watery stools, appendicitis, ileitis, pancreatitis and hepatitis, confusing the diagnosis with other gastrointestinal diseases.

Adverse Reactions to Intravenous Immunoglobulins - Our Experience.

Background: Adverse reactions to intravenous immunoglobulins (IVIG) are divided by organ system involved, or by timing of onset-immediate which occur during infusion usually rate-related, true IgE-mediated anaphylaxis and delayed reaction which occur hours to days after the infusion.

Aim: To describe the adverse events of patients given IVIG infusions.

Methods: Total number of patients receiving IVIG was 41 with 25 males (60.

Depression of neutrophil function followed by severe infection in a child with Marasmic Kwashiorkor.

Malnutrition in childhood continues to be one of the most important risk factor for secondary immunodeficiency in the world; therefore one should think of existence of malnutrition in a child suffering of frequent infections, not only in developing country, rarely but still possible in developed country also. Undernourishment in the early childhood is a trigger for starting a vicious cycle of impaired immunity, recurrent infections, and worsening malnutrition. Taking out from that cycle is an urgent and complex process, in which in parallel the infection should be controlled and the nutritional status solved out, and then, slowly follows the restoration of the immune system.

Genetic and demographic features of X-linked agammaglobulinemia in Eastern and Central Europe: a cohort study.

Primary immunodeficiency disorders are a recognized public health problem worldwide. The prototype of these conditions is X-linked agammaglobulinemia (XLA) or Bruton's disease. XLA is caused by mutations in Bruton's tyrosine kinase gene (BTK), preventing B cell development and resulting in the almost total absence of serum immunoglobulins.

[Feasibilities of cytological diagnosis in the static telepathology mode].

Results of cytological diagnosis in the static telepathology mode are analyzed. Three expert cytologists made the diagnosis on the basis of images of cytological preparations obtained from 94 patients with tumors of soft tissues and bones. A total of 113 diagnoses were correct: benign or malignant type of the tumor and its histological type were identified.

[The potentials of fiber bronchoscopy with immediate cytological study in the diagnosis of lung cancer under outpatient conditions].

Complex examination using fiber bronchoscopy under local anesthesia with urgent cytologic examination of samples was performed in 206 outpatients with clinically suspected lung cancer. Malignancy was diagnosed in 138 cases. Tumor was cytologically confirmed in 95.

[Effect of freezing-thawing on proteolytic activity of soluble and immobilized trypsin].

The proteolytic activity of soluble trypsin was studied after the effect of different freezing-thawing conditions ranging from 0 to 196 degrees C. The enzyme is inactivated most essentially during a slow warming of the preparations under experiment. The trypsin activity decrease is found to depend directly on the number of the freezing-thawing cycles.