The effect of haemopoietic stem cell transplantation on the ocular phenotype in mucopolysaccharidosis type I (Hurler).

Purpose: To determine whether the ocular phenotype in patients with mucopolysaccharidosis type I (MPSI) Hurler is affected by the efficacy of previous haemopoietic stem cell transplantation (HSCT).

Design: A retrospective cohort study of patients with MPSI who had undergone treatment with HSCT.

Methods: Ocular phenotype was documented for each patient and compared to levels of biomarkers representing efficacy of previous transplantation.

Virtual obesity collaborative with and without decision-support technology.

Objective: The purpose of this study was to evaluate school-based health center (SHBC) provider adherence to guidelines for identification and assessment of childhood obesity after participation in a virtual Health Disparities Learning Collaborative with and without HeartSmartKids™, decision-support technology with tailored patient education.

Design And Setting: A cluster randomized comparative effectiveness trial was conducted with 24 SBHCs from six states.

Participants: The sample consisted of 33 SBHC providers and review of medical charts at three time points.