Publications by authors named "Karen Tobias"

Article Synopsis
  • The study looked at dogs with liver tumors to see if their blood clotting times (PT and aPTT) were longer than normal before surgery.
  • Out of 359 dogs, 74 had longer PT or aPTT, and 20 had both, but only dogs with a type of tumor called hemangiosarcoma showed both problems together.
  • The results suggest that testing for these blood clotting times isn't very helpful for most liver tumor dogs, unless there's a strong chance they have hemangiosarcoma.
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Objective: To report the clinical perioperative, short-term, and long-term outcomes for cats undergoing ameroid ring constrictor (ARC) attenuation of a congenital extrahepatic portosystemic shunt (EHPSS).

Study Design: Retrospective case series from a single veterinary teaching hospital (2002-2020).

Animals: Twenty client-owned cats with EHPSS.

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Objective: To report small intestinal herniation through the epiploic foramen in a dog.

Animals: Nine-year-old male castrated Shih Tzu.

Study Design: Case report.

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Background: Knot tying is a key surgical skill for novices, and repetition over several training sessions improves knot tying. This study examined the effects of repetition within a single training session on quality of knotted loops and compared results of novice trainees and experienced surgeons.

Methods: Using 0.

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Objective: To describe repair of perineal hernias in dogs positioned in dorsal recumbency.

Study Design: Retrospective case series.

Sample Population: Twenty-three dogs with perineal hernias treated by herniorrhaphy, with or without adjunctive procedures.

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Objective: To determine long-term outcomes and factors associated with those outcomes in dogs with gastroesophageal intussusception (GEI).

Animals: 36 dogs with GEI evaluated at 16 veterinary hospitals from January 2000 through January 2018.

Procedures: Medical records of included dogs were reviewed to collect information regarding signalment, clinical signs, physical examination findings, blood work and diagnostic imaging results, surgical findings, and outcome.

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Mastery of basic skills is critical for surgical training. Such training is best obtained by experiential learning, which requires an element of self-reflection. Self-reflection is not always an automatic process, however; guidance may be required.

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Objective: To compare glucose concentrations in peripheral venous and capillary blood samples collected from dogs before and after consumption of a meal and measured with a veterinary-specific portable blood glucose meter (PBGM).

Animals: 12 dogs (96 blood samples).

Procedures: A veterinary-specific PBGM was used to measure blood glucose concentrations.

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Objective: To determine the ability to evaluate laryngeal function under sedation with dexmedetomidine alone or in combination with opioids.

Study Design: Randomized, crossover, blinded study.

Animals: Eight adult research hounds weighing 8 to 22.

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Objective: To compare tensile properties of synthetic, absorbable, monofilament suture material before and after incubation in phosphate-buffered saline (PBS).

Study Design: Two sizes (2-0 and 3-0) of Biosyn, Maxon, Monocryl, PDS II, Securocryl, and Securodox were tested.

Sample Population: Ten suture loops per group.

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A 2-year-old, male castrated German shepherd dog was presented to the University of Tennessee Veterinary Medical Center (UTVMC) with periorbital swelling and conjunctival mucopurulent discharge 2 days following removal of a twig from the medial canthus by the owner. Diagnostic imaging was pursued due to the suspicion of a retrobulbar foreign body (FB). A cylindrical FB approximately 3.

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OBJECTIVE To investigate the use of canine whole blood (WB) for measurement of ammonia concentration by use of a point-of-care ammonia meter and to compare results of measuring ammonia concentrations in WB, EDTA-anticoagulated WB, and plasma. ANIMALS 40 client-owned dogs. PROCEDURES A blood sample (2 mL) was obtained from each dog.

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Background: Preanalytic factors such as time and temperature can have significant effects on laboratory test results. For example, ammonium concentration will increase 31% in blood samples stored at room temperature for 30 min before centrifugation. To reduce preanalytic error, blood samples may be placed in precooled tubes and chilled on ice or in ice water baths; however, the effectiveness of these modalities in cooling blood samples has not been formally evaluated.

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An 8-year-old female spayed Dachshund presented with an acute onset of dysuria, dyschezia, and painful perineal protrusion. A perineal hernia was ruled out on digital rectal examination, and blood work was unremarkable. An extremely dilated vagina was identified on computed tomography, and hydrocolpos was suspected.

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Background. Serum bile acids (SBA) are used as a routine screening tool of liver function in dogs. Serum samples are usually shipped to a referral laboratory for quantitative analysis with an enzymatic chemistry analyzer.

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Objective: To evaluate the signalment, clinical signs, treatment, and outcome of dogs with urethral prolapse and identify risk factors associated with prolapse or treatment.

Study Design: Retrospective case series.

Animals: Dogs (n = 48) with urethral prolapse.

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Interest in nonpharmacologic approaches for managing pain continues to grow. The aim of this study was to determine the types of pain-relevant programs offered by senior centers and whether the programs varied by clients' race/ethnicity status and center size. A telephone survey was conducted.

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Objective: To report a modified procedure for perineal urethrostomy (PU) in goats.

Study Design: Case series.

Animals: Adult castrated male pet goats (n = 11) that had recurrence of urinary tract obstruction after one or more surgical procedures for obstructive urolithiasis.

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An 8-yr-old intact female African lion (Panthera leo) presented with a 3-day history of lethargy, anorexia, and vomiting. Hematologic and biochemical abnormalities included a leukocytosis, 41,700/microl (4,700-15,300) with a neutrophilia (37,530/microl; 2,000-9,200) and a left shift (1,250/microl bands; 0-300), and mild hypokalemia of 2.1 mEq/L (2.

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Objectives of this study were to adapt a commercial human protein C (PC) colorimetric assay for use in dogs and to investigate effects of various storage conditions. The human assay was modified by using pooled canine plasma for calibration and by increasing the activation time. PC activity was measured in fresh canine plasma and in plasma stored under various conditions.

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Portosystemic vascular anomalies.

Vet Clin North Am Small Anim Pract

May 2009

Portovascular anomalies are most commonly seen as congenital communications in dogs and cats. Fixation, whether surgical or interventional, should be considered in all cases for which it is possible to improve perfusion to the liver, and ultimately liver function. Medical management before fixation is always recommended.

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Laryngeal paralysis is a common cause of upper airway obstruction in older, large-breed dogs and is likely associated with a generalized polyneuropathy in most animals. Surgical therapy is frequently indicated, and UAL is currently the recommended treatment. Respiratory signs significantly improve in most patients after surgery; however, postoperative complication rates can be high, and patients have a lifelong risk of developing respiratory tract disease.

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Canine inflammatory mammary carcinoma (IMC) is a rare, locally aggressive, highly metastatic tumor that is poorly responsive to treatment. The purposes of this study were to retrospectively evaluate the history, signalment, and clinical signs of dogs with IMC; compare the outcome of affected dogs treated with traditional chemotherapy with those treated with piroxicam; evaluate Cox-2 expression of IMC cells; and correlate Cox-2 expression with outcome based on treatment. Strong cyclooxygenase-2 expression was present in all tumors.

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A 4-year-old, castrated male, mixed-breed dog was evaluated because of progressive head swelling, exercise intolerance, and increasing respiratory effort of 1 month's duration. Physical examination and radiographs revealed severe edema of the head and face that was cranial to a circumferential, midcervical constriction caused by scarring related to previous removal of a foreign body. Surgical en bloc resection of the cicatricial tissue was performed, and clinical signs resolved completely after 2 months.

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Objective: To evaluate trans-splenic portal scintigraphy (TSPS) and per-rectal portal scintigraphy (PRPS) for diagnosis of congenital portosystemic shunts (CPSS) in dogs, and compare these results with surgical findings.

Study Design: Prospective, randomized cross over clinical trial.

Animals: Dogs (n=42) with suspected CPSS.

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