Publications by authors named "Karen Soule"
A reagent-based treatment method was developed for the removal of sodium dodecyl sulfate (SDS) from aqueous dispersions of single-wall carbon nanotubes (SWCNTs). Based on a survey of various reagents, organic solvents emerged as the most effective at interrupting the SDS:SWCNT interaction without producing deleterious side reactions or causing precipitation of the surfactant. Specifically, treatment with acetone or acetonitrile allows for the facile isolation of SWCNTs with near complete removal of SDS through vacuum filtration, resulting in a 100x reduction in processing time.
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- Human leukaemic HL-60 cells are often used to study adhesion molecules due to their ability to mimic white blood cell rolling dynamics.
- Undifferentiated HL-60 cells demonstrated a significant increase in rolling velocity influenced by P-selectin concentration, but DMSO-treated cells showed variable responses depending on treatment duration.
- The study suggests that DMSO-induced changes in HL-60 cells may impact their function in inflammatory response research, making them less reliable as substitutes for actual neutrophils after prolonged differentiation.