Publications by authors named "Karen Sokolov"
Article Synopsis
- bRT before CAR T-cell therapy for LBCL is gaining traction, but its impact on treatment outcomes is unclear.
- A study analyzed 23 LBCL patients who underwent bRT followed by CAR T-cell therapy, focusing on various PET scan metrics to measure tumor response.
- Results revealed that significant decreases in SUV and MTV during bRT were linked to better progression-free survival, freedom from distant progression, and local control.
- The findings suggest that greater cytoreduction via bRT may enhance the effectiveness of subsequent CAR T-cell therapy in treating large B-cell lymphoma.
Background: Bridging therapy (BT) with systemic therapy (ST), radiation therapy (RT), or combined-modality therapy (CMT) is increasingly being utilized prior to chimeric antigen receptor (CAR) T-cell therapy for large B-cell lymphoma (LBCL). We report the long-term outcomes of the patients who received commercial CAR T-cell therapy with or without BT.
Methods: The patients with LBCL who underwent infusion of a commercial CD19 CAR T product were eligible.
As the US transitions from volume- to value-based cancer care, many cancer centers and community groups have joined to share resources to deliver measurable, high-quality cancer care and clinical research with the associated high patient satisfaction, provider satisfaction, and practice health at optimal costs that are the hallmarks of value-based care. Multidisciplinary oncology care pathways are essential components of value-based care and their payment metrics. Oncology pathways are evidence-based, standardized but personalizable care plans to guide cancer care.
View Article and Find Full Text PDFBackground: Community-acquired, methicillin-resistant Staphylococcus aureus (MRSA) infections are on the rise among patients without risk factors for resistant microorganisms. A new, serious community-acquired MRSA manifestation, postpartum iliopsoas pyomyositis is described.
Case: A 24-year-old Hispanic female presented with back pain 9 days after a normal vaginal delivery.