Pulmonary cystic echinococcosis acquired during a short-term tourist travel.

Background: Cystic echinococcosis is non-endemic in Denmark and primarily diagnosed in migrants from endemic areas. Here, we report a case of pulmonary cystic echinococcosis in a Danish woman with no history of longer-term stays abroad, only holiday travelling to tourist destinations. This is the first case reported in international literature from Denmark where the causative parasite was identified to species and genotype level.

Invasive pulmonary aspergillosis and hyperthermia in an immunocompetent patient with COVID-19.

Severely ill influenza patients are at increased risk of invasive pulmonary aspergillosis (IPA). Previous reports suggest that Coronavirus Disease 2019 (COVID-19) patients may also be at increased risk of IPA. Here we present an co-infection in a COVID-19 immunocompetent patient, complicated by bacteremia and persistent hyperthermia.

Treatment of candidemia in a nationwide setting: increased survival with primary echinocandin treatment.

Background: In accordance with international guidelines, primary antifungal treatment (AFT) of candidemia with echinocandins has been nationally recommended in Denmark since 2009. Our nationwide cohort study describes the management of candidemia treatment focusing on the impact of prophylactic AFT on species distribution, the rate of adherence to the recommended national guidelines for AFT, and the effect of AFT on patient outcomes.

Materials And Methods: Incident candidemia cases from a 2-year period, 2010-2011, were included.

Do probiotics prevent colonization with multi-resistant Enterobacteriaceae during travel? A randomized controlled trial.

Background: Travelers to India are often colonized with extended-spectrum beta-lactamase producing Enterobacteriaceae (ESBL-E) or Carbapenemase-producing Enterobacteriaceae (CPE). The aim of this study was to investigate if the probiotic species Lactobacillus Rhamnosus GG (LGG) could prevent the colonization of the gut with multi-drug resistant bacteria.

Methods: Adult Danish travelers traveling to India for 10-28 days were randomized to receive either LGG or no probiotics during travel.

Pediatric Candidemia Epidemiology and Morbidities: A Nationwide Cohort.

Background: Candidemia is the most frequent pediatric fungal infection, but incompletely elucidated in population-based settings. We performed a nationwide cohort study including all pediatric patients with candidemia in Denmark from 2004 to 2014 to determine age, incidence, species distribution, underlying diseases, patient management and outcomes.

Methods: All candidemia episodes were identified through the active nationwide fungemia surveillance program.

Rotavirus is frequent among adults hospitalised for acute gastroenteritis.

Introduction: Rotavirus infection is the most common aetiology of acute gastroenteritis (AGE) among young children. In adults, diagnostics focus mainly on bacterial causes, though recent studies suggest that rotavirus is a frequent agent. The aim of this study was to examine the proportion of rotavirus in adults hospitalised with AGE and to identify possible predictors.

Colonisation with multi-resistant Enterobacteriaceae in hospitalised Danish patients with a history of recent travel: a cross-sectional study.

Background: The global spread of multi-resistant Enterobacteriaceae is a new challenge in health care. Travelling in high endemic areas has been associated with colonisation. This study was performed among patients hospitalised for any reason, with recent travel abroad to identify the rate for colonisation with multi-resistant bacteria.

Early diphtheria-tetanus-pertussis vaccination associated with higher female mortality and no difference in male mortality in a cohort of low birthweight children: an observational study within a randomised trial.

Background: Studies from low-income countries have suggested that diphtheria-tetanus-pertussis (DTP) vaccine provided after Bacille Calmette-Guerin (BCG) vaccination may have a negative effect on female survival. The authors examined the effect of DTP in a cohort of low birthweight (LBW) infants.

Methods: 2320 LBW newborns were visited at 2, 6 and 12 months of age to assess nutritional and vaccination status.

Randomized trial of BCG vaccination at birth to low-birth-weight children: beneficial nonspecific effects in the neonatal period?

Background: Observational studies have suggested that BCG may have nonspecific beneficial effects on survival. Low-birth-weight (LBW) children are not given BCG at birth in Guinea-Bissau; we conducted a randomized trial of BCG at birth (early BCG) vs delayed BCG.

Methods: In the period 2004-2008 we recruited 2320 LBW children in Bissau.

Vitamin A supplementation and BCG vaccination at birth in low birthweight neonates: two by two factorial randomised controlled trial.

Objective: To investigate the effect of vitamin A supplementation and BCG vaccination at birth in low birthweight neonates.

Design: Randomised, placebo controlled, two by two factorial trial.

Setting: Bissau, Guinea-Bissau.