Publications by authors named "Karen Rico"
Abetted by widespread usage of acid-suppressing proton pump inhibitors (PPIs), the mitogenic actions of the peptide hormone gastrin are being revisited as a recurring theme in various gastrointestinal (GI) malignancies. While pathological gastrin levels are intricately linked to hyperplasia of enterochromaffin-like cells leading to carcinoid development, the signaling effects exerted by gastrin on distinct cell types of the gastric mucosa are more nuanced. Indeed, mounting evidence suggests dichotomous roles for gastrin in both promoting and suppressing tumorigenesis.
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- Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are increasingly common in the U.S. and differ in their functions and locations within the gastrointestinal tract.* -
- The study aims to differentiate types of small intestinal neuroendocrine tumors, specifically duodenal gastrinomas (DGASTs), through advanced genomic analyses, including whole exome sequencing and RNA-sequencing.* -
- Findings reveal that DGASTs exhibit changes in gene expression related to mesenchymal and calcium signaling pathways, alongside a lack of immune cells compared to surrounding tissues, suggesting complex interactions in tumor progression.*
Objective: To understand staff and clients' experiences with delivering and receiving nutrition education in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC).
Methods: Focus groups involving WIC staff, clients, and former clients in Arizona. Client and staff perceptions of WIC nutrition education, preferences, and suggestions for improvement were examined.