Publications by authors named "Karen Oliveira Gaester"
IL28B gene polymorphism SNP rs8099917 genotype GG is associated with HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in HTLV-1 carriers.
Tatiane Assone Fernando Vieira de Souza Karen Oliveira Gaester Luiz Augusto Marcondes Fonseca Olinda do Carmo Luiz
PLoS Negl Trop Dis
September 2014
Background: The polymorphisms of IL28B have been described as important in the pathogenesis of infections caused by some viruses. The aim of this research was to evaluate whether IL28B gene polymorphisms (SNP rs8099917 and SNP rs12979860) are associated with HAM/TSP.
Methods: The study included 229 subjects, classified according to their neurological status in two groups: Group I (136 asymptomatic HTLV-1 carriers) and Group II (93 HAM/TSP patients).