Synopsis of recent research by authors named "Karen O Jones"
Karen O Jones' research primarily focuses on pharmacokinetics and biotransformation processes of various drugs, specifically involving prodrugs and peptide hormones.
One of her key studies investigates the biotransformation of prasugrel by human carboxylesterases, revealing the enzymatic mechanisms that activate the prodrug to its effective form, critical for its pharmacological action.
Another significant work characterizes the pharmacokinetics and hepatic extraction of recombinant human parathyroid hormone in different animal models, providing insights into its therapeutic potential and metabolism in various species.
