Publications by authors named "Karen Krogh-Jensen"
Investigation of the presence and antinociceptive function of muscarinic acetylcholine receptors in the African naked mole-rat (Heterocephalus glaber).
J Comp Physiol A Neuroethol Sens Neural Behav Physiol
January 2016
Article Synopsis
- The study explored the cholinergic system in African naked mole-rats, particularly focusing on the M1 and M4 subtypes of muscarinic acetylcholine receptors.
- A comparison of protein sequences revealed 95% similarity with house mice, indicating that naked mole-rats can express all five muscarinic receptor subtypes.
- Pain relief was observed in mole-rats after treatment with specific receptor agonists, suggesting that these receptors play a significant role in reducing pain.