Cavum septi pellucidi in Tourette syndrome.

Background: An enlarged cavum septum pellucidum (CSP) is a putative marker of disturbed brain development, and it has been associated with a variety of neuropsychiatric disorders. The goal of this study was to characterize systematically the CSP and the related cavum vergae in individuals with Tourette syndrome (TS).

Methods: The overall size and anteroposterior length of the CSP in 161 children (97 with TS and 64 normal pediatric control subjects) and 107 adults (43 with TS and 64 normal adult control subjects) were rated on high-resolution magnetic resonance images in the coronal view.