Publications by authors named "Karen Irgens"

Objectives: The aim of this study was to assess the overall prevalence of pulmonary hypertension (PH) in an unselected MCTD cohort and review the current knowledge with a systematic database search.

Methods: A nationwide multicentre cohort of 147 adult MCTD patients were initially screened for PH by echocardiography, high-resolution computed tomography (HRCT), pulmonary function tests and N-terminal pro-brain natriuretic peptide (NT-proBNP) and then followed up for a mean of 5.6 years.

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Background: Mixed connective tissue disease (MCTD) is an immune-mediated, systemic disorder of unknown cause.

Objective: To assess the prevalence, pattern and severity of interstitial lung disease (ILD) in a cross-sectional study of the nationwide, Norwegian MCTD cohort.

Methods: 126 patients with MCTD were systematically examined for ILD by high-resolution CT (HRCT), pulmonary function tests (PFT), 6 min walk test (6MWT) and by the New York Heart Association (NYHA) functional classification of dyspnoea.

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Background: Temporal arteritis is a systemic granulomatous vasculitis affecting large and medium sized arteries. Scalp necrosis is a rare complication that can appear before, during and after treatment.

Material And Methods: A patient with temporal arteritis and scalp necrosis is presented and relevant literature reviewed.

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