Publications by authors named "Karen Hanze-Villavicencio"

Post-artesunate delayed hemolysis (PADH) occurred in 6 of 24 children treated with artesunate for severe malaria in the United States; however, severe hemolysis requiring hospitalization or transfusion was rare. In children in the United States treated with artesunate, counseling, and symptom monitoring may be preferred to weekly laboratory surveillance for PADH.

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Article Synopsis
  • Tuberculous meningitis (TBM) can lead to serious health issues in children and is best diagnosed early using MRI, which can reveal miliary meningeal TB.
  • Two cases are detailed: one is a 9-year-old girl with symptoms like fever and seizures who was found to have TBM through brain MRI and subsequent tests, leading to a four-drug TB treatment.
  • The second case involves a 17-year-old girl with Crohn's disease and persistent ear infections, ultimately diagnosed with TBM, confirmed by various tests including positive cultures for acid-fast bacilli, and treated with a similar four-drug regimen.
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In pregnant people colonized with group B (GBS) in Botswana, we report the presence/expansion of sequence types 223 and 109, a low rate of erythromycin resistance, and 3 novel sequence types. These data highlight the importance of local epidemiologic studies of GBS, a significant source of neonatal disease.

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A 2-year-old, previously healthy, male presented with an insidious history of intermittent left knee pain and edema who had been evaluated in the emergency department on multiple occasions with unremarkable imaging and normal laboratory results. On the day of presentation, he had mild edema of the left knee and inability to bear weight. Synovial fluid analysis showed an elevated white cell count with neutrophil predominance and mildly elevated inflammatory markers, consistent with septic arthritis.

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