Cross-immunity and immune mimicry as mechanisms of resistance to the lantibiotic lacticin 3147.

Lantibiotics are antimicrobial peptides that possess great potential as clinical therapeutic agents. These peptides exhibit many beneficial traits and in many cases the emergence of resistance is extremely rare. In contrast, producers of lantibiotics synthesize dedicated immunity proteins to provide self-protection.

'Things aren't the same, are they?': The management of bad news delivery in the discourse of stroke care.

Health professionals associated with stroke care tend to emphasize the optimistic possibilities for recovery from stroke and downplay its disabling nature. Therefore, unlike in cancer care, the 'bad news' interview is not a recognized part of stroke care. Nevertheless, at some stages in the trajectory of the illness the issue of disability may have to be discussed and this paper concerns one such occasion.