Publications by authors named "Karen Goebes"
Article Synopsis
- Alpha-fetoprotein (AFP) is a fetal protein that is expressed in about 50% of hepatocellular carcinoma cases and has potential as a target for immunotherapy.
- The study focused on identifying AFP-specific T cell populations in the blood of cirrhotic patients, finding varying frequencies of T cells specific for different AFP peptide epitopes.
- T cell clones specific to AFP137 and AFP158 were isolated and characterized, suggesting they could play a role in immunotherapy by helping to monitor dendritic cell loading with peptides.
