Publications by authors named "Karen Few"
Article Synopsis
- The study aimed to compare the immune responses of preterm infants receiving a meningococcal B vaccine using either a 2+1 or a 3+1 vaccination schedule while also evaluating the side effects of routine vaccinations.
- The research was conducted in an open-label, phase IV study format across six hospitals in the UK, enrolling 129 preterm infants born before 35 weeks gestation.
- Results indicated that while both vaccination schedules were effective, the 3+1 schedule led to a significantly higher antibody response against a specific strain compared to the 2+1 schedule, but also resulted in more fever episodes after vaccination.
Next-generation 3-Tesla magnetic resonance (MR) scanners offer improved neonatal neuroimaging, but the greater associated radiofrequency radiation may increase the risk of hyperthermia. Safety data for neonatal 3-T MR scanning are lacking. We measured rectal temperatures continuously in 25 neonates undergoing 3-T brain MR imaging and observed no significant hyperthermic threat.
View Article and Find Full Text PDFLymphocyte subpopulations in premature infants: an observational study.
Arch Dis Child Fetal Neonatal Ed
November 2016
Background And Objectives: The infant's immune system evolves over the first months and years of life. Strong correlation exists between lymphocyte count, lymphocyte subpopulations and gestational age at birth. Associations with antenatal and postnatal steroid treatment, infection and chronic lung disease have also been described.
View Article and Find Full Text PDF'Feed and wrap' or sedate and immobilise for neonatal brain MRI?
Arch Dis Child Fetal Neonatal Ed
September 2015