Objective: Electronic immunization information systems (IISs) are now established in almost all US states. We used the IIS in Minnesota, Georgia, and Connecticut for immunization data and as the source of 1 of 2 control groups to measure pentavalent rotavirus vaccine (RV5) effectiveness (VE) using case-control methodology.
Patients And Methods: Case-subjects were vaccine-eligible children who presented to 1 of 5 hospitals or emergency departments with gastroenteritis and had rotavirus antigen detected in stool during any of 3 rotavirus seasons (2007-2009).
Objectives: We sought to assess Haemophilus influenzae type b (Hib) vaccination coverage in diverse areas of the United States during the 2008-2009 Hib vaccine shortage. Interim recommendations for Hib vaccination during the shortage called for deferral of the booster dose only among children not at high risk for disease; the primary series given during the first year of life continued to be recommended for all children.
Methods: Vaccination data on ∼123,000 children were collected from 8 Immunization Information System (IIS) sentinel sites.
Objectives: The Minnesota Department of Health (MDH) examined hospital practices as recommended by the Advisory Committee on Immunization Practice in 2005 that hepatitis B vaccine should be administered universally to newborn infants prior to hospital discharge and within 12 hours of birth if their mothers test positive or are admitted with unknown status for hepatitis B surface antigen.
Methods: The MDH conducted a survey of perinatal hepatitis B birth dosing policies in Minnesota birthing hospitals, which prompted (1) and investigation of hospital birth dose rates from the Immunization Information System (IIS) and (2) a chart review of three selected hospitals with low rates.
Results: The (IIS) records of children born in Minnesota during 2007 and the first 5 months of 2008 showed a hepatitis B birth dose rate that was lower than expected (2007: 37%; 2008: 48%).