Publications by authors named "Karen D Zeise"
Article Synopsis
- The text discusses a specific fungus that survives in the acidic environment of the human stomach, potentially causing conditions like ulcers and gastritis.
- In research on mice, it was found that this fungus can induce localized gastritis without affecting the intestine, highlighting the stomach's vulnerability to fungal infections.
- The study identified immune responses and gene expressions linked to fungal infection in a specific stomach region, suggesting the importance of further research on how this infection interacts with the host's immune system and microbiota.
Article Synopsis
- Scientists studied how certain bacteria affect stomach inflammation in mice, which can be similar to humans.
- They found that the bacteria caused only a little inflammation but made the stomach produce more helpful substances against infections.
- When the mice had a food allergy, their stomachs showed a strong immune response, but the bacteria didn’t make this response worse.
Emerging studies have highlighted the disproportionate role of Candida albicans in influencing both early community assembly of the bacterial microbiome and dysbiosis during allergic diseases and intestinal inflammation. Nonpathogenic colonization of the human gastrointestinal (GI) tract by C. albicans is common, and the role of this single fungal species in modulating bacterial community reassembly after broad-spectrum antibiotics can be readily recapitulated in mouse studies.
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