Two rare cases of pancreatic adenosquamous carcinoma: A review of the literature with focus on radiologic findings.

Pancreatic adenosquamous carcinoma (PASC) is a rare, aggressive subtype of pancreatic tumor with a poor prognostic outlook compared to the much more common pancreatic adenocarcinoma. Here we present two cases of the rare PASC and analyze the radiologic findings on computed tomography (CT) and 18F- fluorodeoxyglucose positron emission tomography (FDG-PET). Both cases involve 62-year-old women presenting with abdominal pain, nausea, and vomiting who on imaging were found to have infiltrating lobular pancreatic masses with ring enhancement on CT and peripheral hypermetabolism with central necrosis on FDG-PET.