High-Throughput Identification of the Midgut Proteome Unravels a Sophisticated Hematophagic Machinery.

Chagas disease is one of the most common parasitic infections in Latin America, which is transmitted by hematophagous triatomine bugs, of which is the vector prototype for the study of this disease. The protozoan parasite , the etiologic agent of this disease, is transmitted by the vector to humans through the bite wound or mucosa. The passage of the parasite through the digestive tract of its vector constitutes a key step in its developmental cycle.