Publications by authors named "Karen C Rosenspire"

Article Synopsis
  • - Hodgkin lymphoma (HL) is a rare type of cancer that originates from B-cells, with two primary forms: classical HL and nodular lymphocyte-predominant HL.
  • - Recent advancements in treatment have significantly improved cure rates, leading to a focus on minimizing long-term side effects when planning treatment.
  • - The updated NCCN Guidelines for HL highlight two key areas: adjusting radiation therapy doses for better patient management and addressing treatment strategies for advanced-stage or recurring classical HL.
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A 50-year-old woman with stage IV sigmoid adenocarcinoma presented for restaging FDG PET/CT status post neoadjuvant chemotherapy/immunotherapy and diverting sigmoid colostomy. FDG PET/CT demonstrated FDG uptake in the known sigmoid mass and in abdominopelvic lymph node metastases. Bilateral, asymmetric, hypermetabolic axillary lymphadenopathy was also observed, an atypical pattern of spread for colon cancer.

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The NCCN Clinical Practice Guidelines in Oncology for Hodgkin Lymphoma (HL) provide recommendations for the management of adult patients with HL. The NCCN panel meets at least annually to review comments from reviewers within their institutions, examine relevant data, and reevaluate and update their recommendations. Current management of classic HL involves initial treatment with chemotherapy alone or combined modality therapy followed by restaging with PET/CT to assess treatment response.

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