Publications by authors named "Karen Aparecida Farias de Souza"

Enteroviruses (EV) are most common cause of central nervous system (CNS) infection, mainly aseptic meningitis. In Brazil, data available concerning the distribution of EV types are scarce. The aim of this study was to describe of types EV in patients with infection of the CNS in São Paulo State.

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  • * The outbreak occurred from October 26-29, 2015, affecting 28 individuals (22 residents and 6 staff), with an overall attack rate of 25.9% and higher rates in residents (8.5%).
  • * Genetic analysis revealed that a single rotavirus strain was responsible for the outbreak, highlighting the need to consider RVA in investigations and prompting discussions on the potential benefits of RVA vaccines for the elderly.
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  • * G3P[8] was the dominant strain in 2012 and 2013 but drastically decreased in 2014, while G12P[8] initially declined but then rapidly re-emerged to become the predominant strain by mid-2014.
  • * This shift correlates with increased hospitalizations for diarrhea in 2014, suggesting a potential outbreak of G12P[8] and emphasizing the need for ongoing surveillance of rotavirus and vaccine effectiveness in Brazil.
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