Publications by authors named "Karen A Lodermeier"
Introduction/aims: In the Diabetes Control and Complications Trial (DCCT), the minimal nerve conduction (NC) criterion for diabetic sensorimotor polyneuropathy (DSPN) was abnormality of NC in more than one peripheral nerve without specifying the attributes of NCs to be evaluated. In the present study, we assess individual and composite scores of NCs meeting the DCCT criterion and signs for improved diagnosis and assessment of DSPN severity.
Methods: Evaluated were 13 attributes and 6 composite NC scores and signs and symptoms in 395 healthy subjects (HS) and 388 persons with diabetes (DM).
Objective: To evaluate the associated diseases, polyneuropathy correlates, and risk covariates of neuropathic plantar ulcers (PUs) and neuropathic arthropathies (NAs).
Design: The authors conducted a retrospective, observational study over 3.5 years of 69 patients with neuropathy, NA, or PU seen in a wound clinic who also had a comprehensive neurologic evaluation and neurophysiologic testing.
Article Synopsis
- The study evaluates the effectiveness of different assessment tools for polyneuropathy in 100 patients with familial amyloidotic polyneuropathy (FAP), focusing on neurologic signs, neurophysiologic tests, and their correlation with disability and health metrics.
- The modified Neuropathy Impairment Score plus 7 (mNIS+7) proved to be an effective tool for detecting and characterizing various polyneuropathy impairments, showing strong correlations with other measures of health and disability.
- Trained neurologists demonstrated accurate assessments of neuropathy signs using the mNIS+7, which effectively captured the extent of nerve damage in patients with FAP and highlighted small fiber involvement through specialized testing.
Introduction: We assessed proficiency (accuracy and intra- and intertest reproducibility) of smart quantitative sensation tests (smart QSTs) in subjects without and with diabetic sensorimotor polyneuropathy (DSPN).
Methods: Technologists from 3 medical centers using different but identical QSTs independently assessed 6 modalities of sensation of the foot (or leg) twice in patients without (n = 6) and with (n = 6) DSPN using smart computer assisted QSTs.
Results: Low rates of test abnormalities were observed in health and high rates in DSPN.