Publications by Karelina L Groenewegen

Publications by authors named "Karelina L Groenewegen"

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Prevalence of prescribing topical corticosteroids to patients with lichen sclerosus following surgery for vulvar cancer: a survey among gynaecologic oncologists in The Netherlands.

Féline O Voss Karelina L Groenewegen Hester Vermaat Maaike C G Bleeker Marc van Beurden

J Obstet Gynaecol

December 2024

Article Synopsis

Vulvar lichen sclerosus (LS) is a chronic inflammatory condition that can lead to serious complications like differentiated vulvar intraepithelial neoplasia (dVIN) and vulvar squamous cell carcinoma (VSCC), making its management critical especially post-surgery for VSCC.
A survey of 44 gynecologic oncologists in the Netherlands revealed that topical corticosteroids (TCS) are prescribed more frequently for LS patients without a history of VSCC compared to those following surgery for VSCC (86% vs. 52%).
Both patient groups are primarily treated with ultra-potent TCS for symptom relief and to prevent progression to serious conditions, though guidelines on post-surgery LS management remain unclear.

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Persisting symptoms in patients with Hashimoto's disease despite normal thyroid hormone levels: Does thyroid autoimmunity play a role? A systematic review.

Karelina L Groenewegen Christiaan F Mooij A S Paul van Trotsenburg

J Transl Autoimmun

April 2021

Objective: Patients with hypothyroidism due to Hashimoto's disease (HD) may experience persisting symptoms despite normal serum thyroid hormone (TH) levels. Several hypotheses have been postulated to explain these persisting symptoms. We hypothesized that thyroid autoimmunity may play a role.