Current Practice for Transverse Mandibular and Maxillary Discrepancies in the Netherlands: A Web-Based Survey Among Orthodontists and Oral and Maxillofacial Surgeons.

The main objective of this study was to provide an overview of the current practice for transverse mandibular and maxillary discrepancies in the Netherlands using a web-based survey. Orthodontists (ORTHO) and Oral and Maxillofacial Surgeons (OMFS) in the Netherlands were invited to the web-based survey via their professional association. Three cases were presented which could be treated non-surgically and surgically.

Complications in Mandibular Midline Distraction.

Mandibular midline distraction (MMD) is a relatively new surgical technique for correction of transverse discrepancies of the mandible. This study assesses the amount and burden of complications in MMD. A retrospective cohort study was performed on patients who underwent MMD between 2002 and 2014.

Lower Eyelid Malposition Following Orbital Fracture Surgery: A Retrospective Analysis Based on 198 Surgeries.

The aim of this study is to analyze the development of lower eyelid malposition following reconstruction of orbital fractures, in relation to the incisions used for access. A total of 198 surgical orbital floor reconstructions were performed in 175 patients between 2001 and 2011. Preoperative and postoperative presence of lower eyelid malposition of patients was reported.

Hyperbaric oxygen therapy as a prevention modality for radiation damage in the mandibles of mice.

Background: Radiation therapy (RT) as part head and neck cancer treatment often leads to irradiation of surrounding normal tissue, such as mandibular bone. A reduced reparative capacity of the bone can lead to osteoradionecrosis (ORN). Hyperbaric oxygen therapy (HBOT) is used to treat ORN, based on its potential to raise the oxygen tension in tissues.

Morbidity of harvesting the iliac crest inner cortical plate for orbital reconstruction.

Purpose: To evaluate the morbidity associated with harvesting the inner cortical plate of the iliac crest for reconstruction of the orbit.

Patients And Methods: In a retrospective case series study, the medical records of all patients who had undergone orbital reconstruction with bone from the iliac crest from January 2000 to April 2012 at the Erasmus Medical Centre were reviewed. A standardized surgical procedure for harvesting the inner cortical plate of the iliac crest was used for all patients.

Blowout fracture in a 3-year-old.

A 3-year-old patient was referred to the oral and maxillofacial department with a fracture of the orbital floor. Due to the lack of clinical symptoms, a conservative approach was chosen. After 3 weeks, an enophthalmos developed.

The effects of heparan sulphate mimetic RGTA-OTR4120 on irradiated murine salivary glands.

Background: This study focuses on the potential of ReGeneraTing Agent OTR4120 (RGTA-OTR4120) to treat radiation-induced damage of salivary glands. RGTAs are biopolymers designed to mimic the effects of heparan sulphate, thereby stimulation tissue repair and regeneration.

Methods: C3H mice were irradiated with a single dose of 15 Gy in the head and neck region.

Gingival overgrowth in Pompe disease: a case report.

Pompe disease, or glycogen storage disease type 2, is a rare inheritable metabolic disease caused by a deficiency of the lysosomal enzyme acid α-glucosidase. Patients with the classic infantile form of Pompe disease present with symptoms during the first 3 months after birth, and most will die within their first year. Recently, enzyme replacement therapy (ERT) with recombinant human α-glucosidase became commercially available for Pompe disease.

Orbital change following Le Fort III advancement in syndromic craniosynostosis: quantitative evaluation of orbital volume, infra-orbital rim and globe position.

Patients with syndromic craniosynostosis suffering from shallow orbits due to midface hypoplasia can be treated with a Le Fort III advancement osteotomy. This study evaluates the influence of Le Fort III advancement on orbital volume, position of the infra-orbital rim and globe. In pre- and post-operative CT-scans of 18 syndromic craniosynostosis patients, segmentation of the left and right orbit was performed and the infra-orbital rim and globe were marked.

Upper airway changes in syndromic craniosynostosis patients following midface or monobloc advancement: correlation between volume changes and respiratory outcome.

In syndromic craniosynostosis patients, respiratory insufficiency may be a pressing indication to surgically increase the patency of the upper airway by midface or monobloc advancement. In this study the volume changes of the upper airway and the respiratory outcome following midface (Le Fort I or III) or monobloc advancement in ten syndromic craniosynostosis patients are evaluated. Pre- and postoperatively, the airway volume was measured using a semi-automatic region growing method.

Three-dimensional airway changes after Le Fort III advancement in syndromic craniosynostosis patients.

Background: To investigate the changes of upper airway volume in syndromic craniosynostosis patients following Le Fort III advancement, computed tomographic scans were analyzed and related to the amount of advancement.

Methods: In this retrospective study, the preoperative and postoperative computed tomographic scans of 19 patients with syndromic craniosynostosis who underwent Le Fort III advancement were analyzed. In four cases, preoperative polysomnography demonstrated obstructive sleep apnea.

Hyperbaric oxygen therapy in the management of radiation-induced injury in the head and neck region: a review of the literature.

Purpose: Radiotherapy is generally used in the treatment of malignant tumors in the head and neck region. It causes a hypoxic, hypocellular, and hypovascular environment that leads to injury to surrounding normal tissue, both acute and chronic, ranging from xerostomia to osteoradionecrosis. These side effects are debilitating and greatly influence quality of life in these patients.

Continuous versus discontinuous distraction: evaluation of bone regenerate following various rhythms of distraction.

Purpose: To investigate continuous distraction osteogenesis (DO) of the nasal bones in a rabbit model, and to compare data from this continuous DO study with data from a previously conducted discontinuous DO study. In addition, radiographic and ultrasonographic bone-fill scores were determined to investigate whether these scores provided reliable predictive value for the amount of new bone formation in the distraction area.

Materials And Methods: Skeletally mature female New Zealand White rabbits were subjected to distraction of the nasal bones.

Sensory testing of inferior alveolar nerve injuries: a review of methods used in prospective studies.

Purpose: The inferior alveolar nerve (IAN) can be injured during trauma or surgery. So far there is no consensus for evaluating IAN injury. This study aimed to identify a testing method suitable for daily clinical practice which allows us to identify nerve injury, grade its severity, and monitor its recovery.

Relapse and stability of surgically assisted rapid maxillary expansion: an anatomic biomechanical study.

Purpose: This anatomic biomechanical study was undertaken to gain insight into the underlining mechanism of tipping of the maxillary segments during transverse expansion using tooth-borne and bone-borne distraction devices.

Materials And Methods: An anatomic biomechanical study was performed on 10 dentate human cadaver heads using tooth-borne and bone-borne distraction devices.

Results: The amount of tipping of the maxillary halves was greater in the tooth-borne group, but the difference was not significant.

Single versus triple daily activation of the distractor: no significant effects of frequency of distraction on bone regenerate quantity and architecture.

Objectives: To study the effect of two different frequencies of distraction on the quantity and architecture of bone regenerate using micro-computed tomography, and to determine whether radiographic and ultrasonographic bone-fill scores provide reliable predictive value for the amount of new bone in the distraction area.

Material And Methods: Twenty-six skeletally mature rabbits underwent three full days of latency, after which midface distraction was started. Low-frequency group (n=12): a distraction rate of 0.

Experience with the transpalatal distractor in congenital deformities.

The transpalatal distractor is a bone-borne device that should eliminate negative orthodontic side-effects of tooth-borne devices. The literature contains reports of several possible complications of the transpalatal distractor. In this retrospective study its use was evaluated in ten patients with various congenital craniofacial anomalies, including clefts.

A giant osteoma of the mandible: case report.

A 53-year-old patient with a giant osteoma of the right mandible is presented. The clinicopathological features of osteoma of the mandible are discussed and Gardner's syndrome was excluded.

Prevention of halo pin complications in post-cranioplasty patients.

Introduction: Distraction Osteogenesis has been successfully implemented in the treatment of maxillary hypoplasia. By using the Rigid External Distraction device (RED) the maxilla can be advanced without the need for bone grafts, providing more stability to the repositioned maxilla.

Background: The introduction of the RED system in craniofacial surgery has given rise to previously unseen problems.