Moderate drinking: no impact on female fecundity.

Objective: To determine the effect of moderate alcohol intake on probability of conception.

Design: Prospective cohort study.

Setting: Normal healthy women enrolled in an artificial donor insemination program.

Fat and female fecundity: prospective study of effect of body fat distribution on conception rates.

Objectives: To study the effect of body fat distribution in women of reproductive age on fecundity.

Design: Prospective cohort study of all women who had entered a donor insemination programme.

Setting: One fertility clinic serving a large part of the midwest of the Netherlands.

Delaying childbearing: effect of age on fecundity and outcome of pregnancy.

Objectives: To study the age of the start of the fall (critical age) in fecundity; the probability of a pregnancy leading to a healthy baby taking into account the age of the woman; and, combining these results, to determine the age dependent probability of getting a healthy baby.

Design: Cohort study of all women who had entered a donor insemination programme.

Setting: Two fertility clinics serving a large part of The Netherlands.

The study of risk habits in reproductive and perinatal epidemiologic research: the use of a donor inseminated population of women.

In this study we assess whether a population of donor inseminated women (ADI) provides an efficient alternative to an open population of women of reproductive age to study the effects of risk habits (cigarette smoking and alcohol consumption) on reproductive and perinatal health. An ADI population can be prospectively monitored before and after pregnancy; women enter the programme because of their husband's infertility. In the pilot clinic every couple asking for first insemination was requested to fill in a self-administered questionnaire on risk habits and the use of medicine.