Gastroprotection against Rat Ulcers by Sterol Derivative.

Different species belonging to the genus (Acyonaceae) are a rich resource for bioactive secondary metabolites. The literature reveals that the gastroprotective effects of marine secondary metabolites have not been comprehensively studied in vivo. Hence, the present investigation aimed to examine and determine the anti-ulcer activity of 4,24-dimethyl-5-cholest-8,18-dihydroxy,22-en-3-ol () isolated from samples of a species.

UPLC-qTOF-MS Phytochemical Profile and Antiulcer Potential of Rottb. Alcoholic Extract.

has been commonly used as a multi-use medicinal plant in folk medicine worldwide. The objectives of our study were to determine the different metabolites in the Rottb. methanol extract, and to assess its in vivo gastroprotective effect in ethanol-induced gastric ulcer model in rats.

Protective effect of Nigella sativa seeds against lead-induced hepatorenal damage in male rats.

Heavy metals are widely distributed in the environment and some of them occur in food, water, air and tissues even in the absence of occupational exposure. Among of these lead, (Pb) is a hazardous substance to human and animals. The present study was carried out to investigate the possible protective effect of co-administered Nigella sativa seeds on lead acetate-induced rats' toxicity in particularly on liver and kidney.

Clinical benefits of biochemical markers of bone turnover in Egyptian children with chronic liver diseases.

Aim: To investigate the association between serum insulin-like growth factor 1 (IGF-1), osteocalcin, and parathyroid hormone (PTH) levels with the etiology and clinical condition of patients with chronic liver disease.

Methods: Eighty children with hepatocellular damage were divided into 3 groups according to the etiology of disease infection: bilharziasis (9 patients), hepatitis B virus (HBV, 12 patients) and hepatitis C virus (HCV, 29 patients). The Child score index was found as A in 24 patients, B in 22 patients, C in 4 patients.