Background: We evaluated the efficacy of different immunosuppressive regimens in patients with primary membranous nephropathy in a large national cohort.
Methods: In this registry study, 558 patients from 47 centers who were treated with at least one immunosuppressive agent and had adequate follow-up data were included. Primary outcome was defined as complete (CR) or partial remission (PR).
Objective: This study was designed to compare the standard and robotic-assisted laparoscopic donor nephrectomy in terms of perioperative course, short-term postoperative outcome, and to evaluate the effect of surgeon's learning curve on these parameters.
Methods: This was a prospective randomized study including 60 patients (mean age, 47 years; age, 21-72 years; 26 males, 34 females) who had been planned laparoscopic donor nephrectomies in our clinic. For comparison of standard and robot-assisted techniques and to evaluate the impact of learning curve, patients were randomized into three groups by a computer, each group containing 20 patients.
Background: Cardiovascular disease (CVD) is considered a public health burden and most common cause of mortality in all over the world. The latency time for developing CVD may be several decades. the objective of this study was to examine the relationship between body composition and Left Ventriculare Mass Index (LVMI) in newly diognosed hypertensive patients.
View Article and Find Full Text PDFJ Cardiothorac Surg
October 2014
Introduction: Straight sternotomy is the most common access for open heart surgery. Techniques have been proposed for maximizing sternal stability in high-risk patients. This trend implies a growing need for newer surgical techniques.
View Article and Find Full Text PDFTo determine the effect of hyperuricemia and allopurinol therapy on renal functions in chronic kidney disease (CKD) stage 3-4, we studied 96 patients in stage 3-4 CKD (57% male, age 65.3 ± 12.4 years).
View Article and Find Full Text PDFBackground: Elevated oxidative status and reduced antioxidant defence systems in patients with chronic renal failure (CRF) accelerate the prevalence of atherosclerosis and other chronic complications. We aimed to investigate the levels of reactive oxygen, nitrogen species, and antioxidants in patients with end-stage renal disease (ESRD) having hemodialysis and controls and evaluate the factors that might influence the oxidative-antioxidative balance.
Methods: Sixty four patients with ESRD were enrolled in this study.
Curr Ther Res Clin Exp
December 2012
Background: Insulin resistance (IR) is frequently recognized in patients with uremia, and it is thought that IR has a basic role in the pathogenesis of cardiovascular disease.
Objective: To evaluate the effect of IR on cardiovascular risk in non-diabetic patients receiving hemodialysis (HD).
Methods: We performed a cross-sectional observational study that comprised 186 non-diabetic patients receiving HD (95 men; mean [SD] age, 46.
Background/objectives: Cardiovascular abnormalities are common in patients with chronic kidney disease. Visfatin influences lipid metabolism, insulin sensitivity, and cardiovascular health. The aim of this study was to explore the relation of serum visfatin to cardiovascular risk factors in nondiabetic peritoneal dialysis (PD) patients.
View Article and Find Full Text PDFBackground/objectives: Cardiovascular disease begins early in the course of chronic kidney disease (CKD), and the glomerular filtration rate (GFR) is an independent risk factor for it. There is little information on cardiac troponin concentrations in patients with CKD who have not commenced dialysis. Factors associated with this deleterious process are not completely understood, and we aimed to determine associated laboratory abnormalities of increased cardiac troponin T (cTnT) in patients with CKD.
View Article and Find Full Text PDFBackground/objectives: Abdominal fat deposition is represented by means of the conicity index (CI), an anthropometric estimate that models the relative accumulation of abdominal fat. We examined the influence of markers of cardiovascular disease in terms of inflammation and lipid profile and body fat distribution on the progression of renal disease in patients with stable chronic kidney disease (CKD) stages 3-5.
Material And Methods: We studied 104 pre-dialysis CKD patients (64 males, 62%; age 64.
Introduction: Atherosclerosis (AS) and malnutrition are 2 major causes of morbidity and mortality in hemodialysis (HD) patients. A high body fat percentage (BFP) may be paradoxically associated with improved survival in chronic HD patients. We aimed to establish BFP profile of the HD patients by using bioimpedance analysis, body mass index (BMI), and waist/hip ratio (WHR) to find out their association with inflammation and AS.
View Article and Find Full Text PDFIntroduction And Aims: Fatigue is a major determinant for quality of life for patients undergoing chronic hemodialysis (HD) treatment. The aim of this study was to determine the severity and contributing factors of fatigue in patients under chronic HD treatment.
Methods: 154 end-stage renal disease (ESRD) patients under HD treatment (92 M, 62 F, mean age 53 ± 15 y, mean duration of HD treatment 92 ± 65 months) were enrolled.
Background: Chronic kidney disease (CKD) is a common problem in long-term survivors after liver transplantation (LT). It is important to identify and correct risk factors that negatively affect kidney function. The purpose of this study was to delineate the risk factors associated with progressive kidney dysfunction after OLT.
View Article and Find Full Text PDFBackground: Although osteopontin (OPN) is a local inhibitor of calcification, it may also be an indirect marker of ongoing systemic calcification. There are few data about clinical and laboratory parameters associated with serum OPN levels in renal transplant (RT) patients. We investigated the relationship between insulin resistance and calcification parameters as estimated with OPN after RT.
View Article and Find Full Text PDFBackground: There are limited data about ambulatory blood pressure monitoring (ABPM) in renal transplantation patients. We sought to evaluate the clinical outcomes, and success of antihypertensive therapy based upon ABPM data.
Methods: We performed ABPM on 82 recipients between 2000 and 2006 including 27 females of overall age of 37.
Background: Renal transplantation is the ideal renal replacement therapy in patients with end-stage renal disease. It was unclear whether a difference in dialysis modality influences outcomes after kidney transplantation. Therefore, we evaluated the influence of dialysis modality.
View Article and Find Full Text PDFBackground: Free triiodothyronine (FT3) is a marker of comorbidity in end-stage renal disease and in many acute and chronic diseases. The objective of the present study was to investigate the effects of pretransplantation FT3 concentration on graft function.
Materials And Methods: Between 2003 and 2008, the study enrolled 86 patients who underwent renal transplantation.
Background: A chronic inflammatory state is a prominent feature in patients with end-stage renal disease (ESRD) who are undergoing maintenance hemodialysis (MHD). "Malnutrition Inflammation Score" (MIS) is a comprehensive scoring system that measures nutrition and inflammation in MHD patients. Inflammation and malnutrition are important risk factors in ESRD patients with pulmonary diseases.
View Article and Find Full Text PDFTransplant Proc
September 2009
The metabolic syndrome (MS) is a known cardiovascular risk factor in the general population and a common problem among renal transplant recipients. This study investigated whether MS after renal transplantation affected long-term graft function. We included 112 transplants at our center between 2000 and 2002.
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