Histopathological Profile of Central Nervous System Tumors in a Peripheral Tertiary Care Centre of West Bengal.

 Central nervous system (CNS) tumor incidence is very low in comparison to other organ neoplasm. Recent increase in the incidence may be due to exposure of the population to various risk factors, genetic mutation, or improved diagnosis with advancement in diagnostic modalities. This study aims to observe the histopathological spectrum of CNS tumors with their clinical profile and basic demography at a single center in a peripheral region in West Bengal.

Simultaneous knockdown of uPA and MMP9 can reduce breast cancer progression by increasing cell-cell adhesion and modulating EMT genes.

In cancer progression, proteolytic enzymes like serine proteases and metalloproteinases degrade the basement membrane enabling the tumor cells to invade the adjacent tissues. Thus, invasion and metastasis are augmented by these enzymes. Simultaneous silencing of uPA and MMP9 in breast cancer cells decreased the wound healing, migratory, invasive and adhesive capacity of the cells.

A rare case of primary renal hydatid cyst presenting with hydatiduria.

Hydatid disease caused by Echinococcus granulosus involves liver in 75 % of cases and lung in 15 % of cases. But primary renal involvement without liver and lung involvement is a very rare event. Among these patients of renal hydatidosis, hydatiduria is seen only in 10-20 % cases, which is considered to be pathognomonic.

Preoperative cytological diagnosis of malignant mesothelioma of tunica vaginalis.

Malignant mesothelioma of tunica vaginalis testis is a rare aggressive neoplasm with ∼200 cases reported so far. A correct preoperative diagnosis of this rare tumor is difficult. Fine-needle aspiration cytology (FNAC) is a rapid and inexpensive diagnostic tool that may prove helpful in such cases.

Annular elastolytic giant cell granuloma of conjunctiva: a case report.

Annular elastolytic giant cell granuloma is a condition characterized histologically by damaged elastic fibers associated with preponderance of giant cells along with absence of necrobiosis, lipid, mucin, and pallisading granuloma. It usually occurs on sun-damaged skin and hence the previous name actinic granuloma. A similar process occurs on the conjunctiva.

Prognostic value of AgNOR in benign and malignant lesions of larynx in a rural medical college hospital, Burdwan, West Bengal.

AgNOR counting is a useful proliferative marker in different malignant lesions and it also acts as a good prognostic indicator in rural hospital. Fifty-three cases of benign and malignant lesions of larynx were examine using AgNOR distribution in routinely processed paraffin embedded histological tissue sections. Significant differences were found between benign lesion, dysplasia (p > 0.