Study on the Bioactivity Response of the Newly Developed Zn-Cu-Mn/Mg Alloys for Biodegradable Implant Application.

Scaffolds play a crucial role in bone tissue engineering to support the defect area through bone regeneration and defect reconstruction. Promising tissue regeneration without negative repercussions and avoidance of the lifelong presence inside the body make bioresorbable metals prosper in the field of regenerative medicine. Recently, Zn and its alloys have emerged as promising biodegradable materials for their moderate degradation rate and satisfactory biocompatibility.

Feasibility Insights of the Green-Assisted Calcium-Phosphate Coating on Biodegradable Zinc Alloys for Biomedical Application: In Vitro and In Vivo Studies.

In the field of bone tissue engineering, recently developed Zn alloy scaffolds are considered potential candidates for biodegradable implants for bone regeneration and defect reconstruction. However, the clinical success of these alloys is limited due to their insufficient surface bioactivities. Further, the higher concentration of Zn produced during degradation promotes antibacterial activity, but deteriorates osteogenic properties.

Electrophoretic Deposition of 58S Bioactive Glass- Polymer Composite Coatings on 316L Stainless Steel: An Optimization for Corrosion, Bioactivity, and Cytocompatibility.

This study presents a facile fabrication of 58S bioactive glass (BG)-polymer composite coatings on a 316L stainless steel (SS) substrate using the electrophoretic deposition technique. The suspension characteristics and deposition kinetics of BG, along with three different polymers, namely ethylcellulose (EC), poly(acrylic acid) (PAA), and polyvinylpyrrolidone (PVP), have been utilized to fabricate the coatings. Among all coatings, 58S BG and EC polymers are selected as the final composite coating (EC6) owing to their homogeneity and good adhesion.

Biosurfactant-Assisted Cu Doping of Brushite Coatings: Enhancing Structural, Electrochemical, and Biofunctional Properties.

Stainless steel (316L SS) has been widely used in orthopedic, cardiovascular stents, and other biomedical implant applications due to its strength, corrosion resistance, and biocompatibility. To address the weak interaction between steel implants and tissues, it is a widely adopted strategy to enhance implant performance through the application of bioactive coatings. In this study, Cu-doped brushite coatings were deposited successfully through pulse electrodeposition on steel substrates facilitated with a biosurfactant (BS) (i.

Development of Zn-2Cu-Mn/Mg Alloys for Orthopedic Applications: Mechanical Performance to In Vitro Degradation under Different Physiological Environments.

Zinc (Zn) and its alloys are considered futuristic biodegradable materials for their acceptable mechanical properties, suitable corrosion rate, and good biocompatibility. In this study, we report newly developed biodegradable Zn-2CuMn/Mg ( = 0, 0.1, and 0.

Influence of Copper on the Microstructural, Mechanical, and Biological Properties of Commercially Pure Zn-Based Alloys for a Potential Biodegradable Implant.

Three Zn-based alloys (Zn1Cu, Zn2Cu, and Zn3Cu) were developed by the addition of Cu (1, 2, and 3 wt %) into commercially pure Zn. This report systematically investigates the potential for these newly developed Zn-based alloys as biodegradable materials. Microstructural studies reveal the presence of spherical-shaped nanosized precipitates of ε-CuZn in the Zn1Cu alloy, whereas Zn2Cu and Zn3Cu alloys exhibit the presence of both micron- and nanosized precipitates of ε-CuZn.

Electrodeposited functionally graded coating inhibits Gram-positive and Gram-negative bacteria by a lipid peroxidation mediated membrane damage mechanism.

The current work deals with a time-dependent study to track the antibacterial action of electrodeposited Cu, Cu-SiC functionally graded coating (FGC) against Escherichia coli NCIM 2931 (Gram-negative) and Bacillus subtilis NCIM 2063 (Gram-positive). After 24 h of incubation, the Cu, Cu-SiC FGC causes 7 Escherichia coli NCIM 2931 and 10 Bacillus subtilis NCIM 2063 log reduction of planktonic cells. The outer membrane permeabilization experiment proves that the intake of excessive Cu ions leads to the damage of bacterial cell membrane followed by lipid degradation.

Synthesis of calcium hydrogen phosphate and hydroxyapatite coating on SS316 substrate through pulsed electrodeposition.

The orthopaedic implants for human body are generally made of different biomaterials like stainless steels or Ti based alloys. However, it has been found that from surface properties point of view, none of these materials is attractive for fast tissue or cell growth on the surface of implant. This is one of the most important criteria to assure quick bonding between implant and body tissues vis-à-vis minimum recovery time for the patient.

Influence of sodium saccharin on the microstructure of pulse electrodeposited Ni-CeO2 nanocomposite coating.

In the present study the Ni-CeO2 nanocomposite coating has been pulse electrodeposited from a watt's type bath containing 30 g/l CeO2 nanoparticles and varying amount of sodium saccharin (SS). Experimental results show that both the amount of codeposited CeO2 particle and crystallite size of Ni in the composite coating decrease with an increase in the SS concentration of the electrolyte. The microhardness increases up to 0.

Synthesis and characterization of pulse co-electrodeposited nickel/ceria nanocomposites.

Nanocrystalline nickel matrix composites reinforced with the nanosized ceria particles have been synthesized by cathodic pulsed electrodeposition. The reinforcement is synthesized by the high energy ball milling (HEBM) technique. Both the reinforcement and composites have been characterized by XRD, TEM and SEM coupled with EDS.

Effect of current density on the microstructure and hardness of Ni-CeO2 nanocomposite coating synthesized by pulse electrodeposition technique.

The Ni-CeO2 nanocomposite coatings have been synthesized by pulse electrodeposition technique with different current densities (0.10, 0.30, 0.

Pulsed co-electrodeposition and characterization of Ni-based nanocomposites reinforced with combustion-synthesized, undoped, tetragonal-ZrO(2) particulates.

Nanostructured nickel matrix composites reinforced with nanosized, undoped, tetragonal zirconia has been synthesized by cathodic pulsed electrodeposition. The reinforcement is synthesized by the aqueous combustion synthesis route with glycine as the fuel and zirconyl nitrate as the oxidizer. The reinforcement and composite have been characterized by XRD, TEM and SEM coupled with EDS.

Synthesis and characterization of Al-Zn/Al2O3 nano-powder composites.

Composites consisting of Al-Zn/Al2O3 have been synthesized using high energy mechanical milling. High energy ball milling increases the sintering rate of the composite powder due to increased diffusion rate. Owing to the finer microstructure, the hardness of the sintered composite produced by using the mechanically milled nanocomposite powder is significantly higher than that of the sintered composite produced by using the as-mixed powder.